Add to ORKGUnder inflammatory conditions, inflammatory cells release reactive oxygen species (ROS) and reactive nitrogen species (RNS) which cause DNA damage. If not appropriately repaired, DNA damage leads to gene mutations and genomic instability. DNA damage checkpoint factors (DDCF) and DNA damage repair factors (DDRF) play a vital role in maintaining genomic integrity. However, how DDCFs and DDRFs are modulated under physiological and pathological conditions are not fully known. We took an experimental database analysis to determine the expression of 26 DNA D
markdownabstract__Abstract__ The crucial factor for the survival of an organism resides in geneti...
The Ddc1/Rad17/Mec3 complex and Rad24 are DNA damage checkpoint components with limited homology to ...
For this eBook, and the associated Research Topic in Frontiers in Genetics, entitled: ‘Cancer-associ...
<p>Under inflammatory conditions, inflammatory cells release reactive oxygen species (ROS) and react...
All living organisms are continually exposed to various environmental stressors, be they anthropogen...
Open accessWhen a human cell detects damaged DNA, it initiates the DNA damage response (DDR) that pe...
Organisms are continuously exposed to DNA damaging agents, consequently, cells have developed an int...
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biological Engineering, 2018Cat...
DNA damage repair (DDR) pathways modulate cancer risk, progression, and therapeutic response. We sys...
During our lifetime, the genome is constantly being exposed to different types of damage caused eith...
The term “the DNA damage response” (DDR) encompasses a sophisticated array of cellular initiatives s...
The DNA damage response (DDR) is essential for maintaining the genomic integrity of the cell, and it...
All cellular organisms contain genomic DNA which provides the instructions for their correct develop...
SUMMARY DNA damage repair (DDR) pathways modulate cancer risk, progression, and therapeutic response...
Genetic alterations such as mutations, genomic rearrangements and aneuploidy, are commonly observed ...
markdownabstract__Abstract__ The crucial factor for the survival of an organism resides in geneti...
The Ddc1/Rad17/Mec3 complex and Rad24 are DNA damage checkpoint components with limited homology to ...
For this eBook, and the associated Research Topic in Frontiers in Genetics, entitled: ‘Cancer-associ...
<p>Under inflammatory conditions, inflammatory cells release reactive oxygen species (ROS) and react...
All living organisms are continually exposed to various environmental stressors, be they anthropogen...
Open accessWhen a human cell detects damaged DNA, it initiates the DNA damage response (DDR) that pe...
Organisms are continuously exposed to DNA damaging agents, consequently, cells have developed an int...
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biological Engineering, 2018Cat...
DNA damage repair (DDR) pathways modulate cancer risk, progression, and therapeutic response. We sys...
During our lifetime, the genome is constantly being exposed to different types of damage caused eith...
The term “the DNA damage response” (DDR) encompasses a sophisticated array of cellular initiatives s...
The DNA damage response (DDR) is essential for maintaining the genomic integrity of the cell, and it...
All cellular organisms contain genomic DNA which provides the instructions for their correct develop...
SUMMARY DNA damage repair (DDR) pathways modulate cancer risk, progression, and therapeutic response...
Genetic alterations such as mutations, genomic rearrangements and aneuploidy, are commonly observed ...
markdownabstract__Abstract__ The crucial factor for the survival of an organism resides in geneti...
The Ddc1/Rad17/Mec3 complex and Rad24 are DNA damage checkpoint components with limited homology to ...
For this eBook, and the associated Research Topic in Frontiers in Genetics, entitled: ‘Cancer-associ...