Interferon regulatory factor 5 (IRF5) is a member of the IRF family of transcription factors. IRF5 was first identified and characterized as a transcriptional regulator of type I interferon expression after virus infection. In addition to its critical role(s) in the regulation and development of host immunity, subsequent studies revealed important roles for IRF5 in autoimmunity, cancer, obesity, pain, cardiovascular disease, and metabolism. Based on these important disease-related findings, a large number of commercial antibodies have become available to study the expression and function of IRF5. Here we validate a number of these antibodies for the detection of IRF5 by immunoblot, flow cytometry, and immunofluorescence or immunohistochemis...
BACKGROUND: Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by the ...
PURPOSE: IRF-5 is a direct transducer of virus-mediated and TLR-mediated signaling pathways for the ...
BACKGROUND: Interferon regulatory factor (IRF) family members have been implicated as critical trans...
Interferon regulatory factor 5 (IRF5) is a member of the IRF family of transcription factors. IRF5 w...
Background: Polymorphisms in the interferon regulatory factor 5 (IRF5) gene are associated with susc...
The interferon regulatory factor 5 (IRF5) gene encodes a transcription factor that plays an importan...
The fulltext of this publication will be made publicly available after relevant embargo periods have...
Gain-of-function polymorphisms in the gene encoding human interferon regulatory factor-5 (IRF5) are ...
The Interferon regulatory factors (IRFs) are a family of transcription factors that play pivotal rol...
IRF5 is a member of the Interferon Regulatory Factor (IRF) family of transcription factors activated...
Copyright © 2012 Candace M. Cham et al. This is an open access article distributed under the Creativ...
Interferon regulatory factor 5 (IRF-5) plays an important role in the innate antiviral and inflammat...
Although the role of human IRF-5 in antiviral and inflammatory responses in vitro has been well char...
Review on IRF1 (interferon regulatory factor 1), with data on DNA, on the protein encoded, and where...
© 2018 De, Zhang, Shih, Singh, Winkler, Donnelly and Barnes. Upon recognition of antigen, B cells un...
BACKGROUND: Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by the ...
PURPOSE: IRF-5 is a direct transducer of virus-mediated and TLR-mediated signaling pathways for the ...
BACKGROUND: Interferon regulatory factor (IRF) family members have been implicated as critical trans...
Interferon regulatory factor 5 (IRF5) is a member of the IRF family of transcription factors. IRF5 w...
Background: Polymorphisms in the interferon regulatory factor 5 (IRF5) gene are associated with susc...
The interferon regulatory factor 5 (IRF5) gene encodes a transcription factor that plays an importan...
The fulltext of this publication will be made publicly available after relevant embargo periods have...
Gain-of-function polymorphisms in the gene encoding human interferon regulatory factor-5 (IRF5) are ...
The Interferon regulatory factors (IRFs) are a family of transcription factors that play pivotal rol...
IRF5 is a member of the Interferon Regulatory Factor (IRF) family of transcription factors activated...
Copyright © 2012 Candace M. Cham et al. This is an open access article distributed under the Creativ...
Interferon regulatory factor 5 (IRF-5) plays an important role in the innate antiviral and inflammat...
Although the role of human IRF-5 in antiviral and inflammatory responses in vitro has been well char...
Review on IRF1 (interferon regulatory factor 1), with data on DNA, on the protein encoded, and where...
© 2018 De, Zhang, Shih, Singh, Winkler, Donnelly and Barnes. Upon recognition of antigen, B cells un...
BACKGROUND: Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by the ...
PURPOSE: IRF-5 is a direct transducer of virus-mediated and TLR-mediated signaling pathways for the ...
BACKGROUND: Interferon regulatory factor (IRF) family members have been implicated as critical trans...