Ribosome stalling results in the production of truncated proteins that can cause proteotoxic stress if not efficiently degraded. A recent paper by Izawa et al. (2017) identifies Vms1 as a key player in the regulation of ribosome quality control specifically on mitochondria-localized ribosomes, ultimately preventing protein aggregate accumulation within mitochondria
AbstractOne of the critical problems with the combustion of sugar and fat is the generation of cellu...
Significance: Mitochondria are complex dynamic organelles pivotal for cellular physiology and human ...
Eukaryotic cells are subdivided into membrane-bound compartments specialized in different cellular f...
Eukaryotic cells have evolved extensive protein quality-control mechanisms to remove faulty translat...
ABSTRACT Mitochondrial dysfunction is associated with the development of many age-relat-ed human dis...
Ribosome-associated quality control (RQC) provides a rescue pathway for eukaryotic cells to process ...
Eukaryotic cells employ the ribosome-associated quality control complex (RQC) to maintain homeostasi...
honors thesisCollege of ScienceBiologyJared RutterAlthough mitochondrial dysfunction has been linked...
dissertationProgressive mitochondrial dysfunction is central to the development ofmany human patholo...
Maintenance of mitochondrial function during stress conditions is vital for cellular survival. In th...
Mitochondria have a compartmentalized gene expression system dedicated to the synthesis of membrane ...
Proteotoxicity has long been considered a key factor in mitochondrial dysfunction and human disease....
The mitochondrial proteome contains proteins from two different genetic systems. Proteins are either...
The human mitochondrial ribosome (mitoribosome) and associated proteins regulate the synthesis of 13...
Mitochondria are essential constituents of a eukaryotic cell by supplying ATP and contributing to ma...
AbstractOne of the critical problems with the combustion of sugar and fat is the generation of cellu...
Significance: Mitochondria are complex dynamic organelles pivotal for cellular physiology and human ...
Eukaryotic cells are subdivided into membrane-bound compartments specialized in different cellular f...
Eukaryotic cells have evolved extensive protein quality-control mechanisms to remove faulty translat...
ABSTRACT Mitochondrial dysfunction is associated with the development of many age-relat-ed human dis...
Ribosome-associated quality control (RQC) provides a rescue pathway for eukaryotic cells to process ...
Eukaryotic cells employ the ribosome-associated quality control complex (RQC) to maintain homeostasi...
honors thesisCollege of ScienceBiologyJared RutterAlthough mitochondrial dysfunction has been linked...
dissertationProgressive mitochondrial dysfunction is central to the development ofmany human patholo...
Maintenance of mitochondrial function during stress conditions is vital for cellular survival. In th...
Mitochondria have a compartmentalized gene expression system dedicated to the synthesis of membrane ...
Proteotoxicity has long been considered a key factor in mitochondrial dysfunction and human disease....
The mitochondrial proteome contains proteins from two different genetic systems. Proteins are either...
The human mitochondrial ribosome (mitoribosome) and associated proteins regulate the synthesis of 13...
Mitochondria are essential constituents of a eukaryotic cell by supplying ATP and contributing to ma...
AbstractOne of the critical problems with the combustion of sugar and fat is the generation of cellu...
Significance: Mitochondria are complex dynamic organelles pivotal for cellular physiology and human ...
Eukaryotic cells are subdivided into membrane-bound compartments specialized in different cellular f...