Aminocyclitols are of interest as glucosidase inhibitors, as probes for the study of pseudoglycosyltransferases, and as potential therapeutics for the treatment of Gaucher’s disease. The synthesis of these targets was reviewed in early 2008, and the aim of this review is to cover material relevant to the synthesis of aminocyclitols since that time. While not a focus of this review, biological evaluation of compounds will be presented where it is recorded in the literature
[[abstract]]In continuation of our interest in the synthesis of glycosidase inhibitors, we report he...
AbstractBackground: Oligosaccharide processing enzymes are important classes of catalysts involved i...
BackgroundGlycosidases are involved in several metabolic pathways and the development of inhibitors ...
Aminocyclitols are of interest as glucosidase inhibitors, as probes for the study of pseudoglycosylt...
Aminocyclitols comprise an important group of compounds with remarkable biological activities. From ...
An efficient fructose-1,6-bisphosphate aldolase mediated synthesis of new aminocyclitol analogues of...
[[abstract]]Efficient syntheses of four aminocyclitols are reported. Each synthesis is accomplished ...
Glycosidases are enzymes involved in many biological processes. In consequence, their inhibitors hav...
A series of gibberellic acid-based aminodiols was designed and synthesized from commercially availab...
Les glycosidases sont des enzymes impliquées dans de nombreux processus biologiques. Entre autres, e...
The synthesis of 3- and 6- aminosugars from the old route requires many synthetic steps and is chall...
New syntheses of a range of aminocyclitols, of the aminocarbasugar and 'confused' aminocarbasugar ty...
Amino-myo-inositol derivatives have been found to be potent inhibitors of glucocerebrosidase (GCase)...
A series of conformationally locked C-glycosides based on the 3-aminopyrano[3,2-b]pyrrol-2(1H)-one (...
L’objectif de mon projet de thèse était de synthétiser différentes familles d’iminosucres comme chap...
[[abstract]]In continuation of our interest in the synthesis of glycosidase inhibitors, we report he...
AbstractBackground: Oligosaccharide processing enzymes are important classes of catalysts involved i...
BackgroundGlycosidases are involved in several metabolic pathways and the development of inhibitors ...
Aminocyclitols are of interest as glucosidase inhibitors, as probes for the study of pseudoglycosylt...
Aminocyclitols comprise an important group of compounds with remarkable biological activities. From ...
An efficient fructose-1,6-bisphosphate aldolase mediated synthesis of new aminocyclitol analogues of...
[[abstract]]Efficient syntheses of four aminocyclitols are reported. Each synthesis is accomplished ...
Glycosidases are enzymes involved in many biological processes. In consequence, their inhibitors hav...
A series of gibberellic acid-based aminodiols was designed and synthesized from commercially availab...
Les glycosidases sont des enzymes impliquées dans de nombreux processus biologiques. Entre autres, e...
The synthesis of 3- and 6- aminosugars from the old route requires many synthetic steps and is chall...
New syntheses of a range of aminocyclitols, of the aminocarbasugar and 'confused' aminocarbasugar ty...
Amino-myo-inositol derivatives have been found to be potent inhibitors of glucocerebrosidase (GCase)...
A series of conformationally locked C-glycosides based on the 3-aminopyrano[3,2-b]pyrrol-2(1H)-one (...
L’objectif de mon projet de thèse était de synthétiser différentes familles d’iminosucres comme chap...
[[abstract]]In continuation of our interest in the synthesis of glycosidase inhibitors, we report he...
AbstractBackground: Oligosaccharide processing enzymes are important classes of catalysts involved i...
BackgroundGlycosidases are involved in several metabolic pathways and the development of inhibitors ...