The C3–C9 segment, (−)-16, of the polyene macrolide antibiotic protomycinolide IV (1a) was prepared in optically pure form from commercially available methyl (S)-2-methyl-3-hydroxypropionate in 12 steps giving 17% yield
The enantioselective total synthesis of spirofungins A (1) and B (2) is reported in 14 steps over th...
The first enantioselective total synthesis of fidaxomicin, also known as tiacumicin B or lipiarmycin...
A chiral-pool-based synthesis of the platensimycin core was achieved using (S)-lactic acid as an ine...
The C11–C17 segment of the antifungal agent soraphen A1α was prepared from glyceraldehyde acetonide ...
The total synthesis of the 16-membered macrolide mycinamicin IV is outlined, which complements our p...
Couchioplanes caeruleus DSM43634 synthesises 67–121C, an aromatic heptaene macrolide that contains a...
Synthesis of the C1-C6 and C7-C23 fragments of the proposed structure of iriomoteolide 1a has been a...
By appropriate dissection of the macrocyclic lactone ring of methymycin erythromycins A and B, picro...
Methodology for the synthesis of the C7–C13 segment (19) and C14–C24 segment (41) of macrolactin A h...
The enantioselective synthesis of the carbon skeleton of 6-deoxyerythronolide B has been achieved in...
The synthesis of the macrolide antibiotic (+/-)-pyrenophorin (1) is described. The molecular sieve p...
The C1-C8 tetrahydropyran and the C17-C24 dihdropyran segments of ambruticin were prepared from L-ar...
The first part of this dissertation describes the revised stereochemical assignment of the cytotoxic...
The dihydropyranyl segment common to ambruticin and jerangolid A was prepared in six steps (31.7% yi...
This thesis consists of five sections. The first four discuss chemistry that is relevant to a total ...
The enantioselective total synthesis of spirofungins A (1) and B (2) is reported in 14 steps over th...
The first enantioselective total synthesis of fidaxomicin, also known as tiacumicin B or lipiarmycin...
A chiral-pool-based synthesis of the platensimycin core was achieved using (S)-lactic acid as an ine...
The C11–C17 segment of the antifungal agent soraphen A1α was prepared from glyceraldehyde acetonide ...
The total synthesis of the 16-membered macrolide mycinamicin IV is outlined, which complements our p...
Couchioplanes caeruleus DSM43634 synthesises 67–121C, an aromatic heptaene macrolide that contains a...
Synthesis of the C1-C6 and C7-C23 fragments of the proposed structure of iriomoteolide 1a has been a...
By appropriate dissection of the macrocyclic lactone ring of methymycin erythromycins A and B, picro...
Methodology for the synthesis of the C7–C13 segment (19) and C14–C24 segment (41) of macrolactin A h...
The enantioselective synthesis of the carbon skeleton of 6-deoxyerythronolide B has been achieved in...
The synthesis of the macrolide antibiotic (+/-)-pyrenophorin (1) is described. The molecular sieve p...
The C1-C8 tetrahydropyran and the C17-C24 dihdropyran segments of ambruticin were prepared from L-ar...
The first part of this dissertation describes the revised stereochemical assignment of the cytotoxic...
The dihydropyranyl segment common to ambruticin and jerangolid A was prepared in six steps (31.7% yi...
This thesis consists of five sections. The first four discuss chemistry that is relevant to a total ...
The enantioselective total synthesis of spirofungins A (1) and B (2) is reported in 14 steps over th...
The first enantioselective total synthesis of fidaxomicin, also known as tiacumicin B or lipiarmycin...
A chiral-pool-based synthesis of the platensimycin core was achieved using (S)-lactic acid as an ine...