Add to ORKGCell delivery is a promising treatment for cardiac repair; however it is limited by low cellular engraftment rates. With this limitation, we propose the use of fibrin microthreads as a mechanism for localized cellular delivery. The purpose of this project was to design a system to increase cell density on biological microthreads for use in cell assisted cardiovascular regeneration. The final design consisted of a dynamic seeding method paired with bundled microthreads, yielding 648+/-234cells/mm; indicative of a confluent cellular monolayer
It is difficult to predict the toxic effects of pesticides on humans because traditional 2D cell cul...
Electrodialysis (ED) is an established technology used to transport small ions from one solution to ...
It is thought that stem cells hold promise for use in future therapeutics. One such application is ...
Atrioventricular (AV) nodal block contributes to cardiovascular disease causing over 2,150 deaths in...
Myocardial infarction afflicts millions of people. Infarcted heart tissue leaves patients with dysfu...
The Gaudette Laboratory’s fibrin sutures deliver stem cells to infarcted myocardium with high engraf...
This project developed a mechanical model for simulating blood flow through the abdominal aorta and ...
The goal of this project was to study the effect of low vimentin levels on the structure, mechanics,...
Currently there is an urgent clinical need for small diameter vascular grafts. Tissue engineered blo...
Cyclic mechanical loading improves strength and extracellular matrix (ECM) synthesis in tissue engin...
Electronic pacemakers are widely used to treat cardiac pacing problems, but the devices have inheren...
Several studies have shown that human mesenchymal stem cells (hMSCs)have the potential to be the fut...
Currently, infallible cancer treatment has not been achieved. Doxorubicin (DOX), an active anticance...
Severe burn injuries lead to significant morbidity and mortality as they are traumatic and affect ne...
Pressure ulcers occur when the tissue has capillary occlusion leading to necrosis and ultimately an ...
It is difficult to predict the toxic effects of pesticides on humans because traditional 2D cell cul...
Electrodialysis (ED) is an established technology used to transport small ions from one solution to ...
It is thought that stem cells hold promise for use in future therapeutics. One such application is ...
Atrioventricular (AV) nodal block contributes to cardiovascular disease causing over 2,150 deaths in...
Myocardial infarction afflicts millions of people. Infarcted heart tissue leaves patients with dysfu...
The Gaudette Laboratory’s fibrin sutures deliver stem cells to infarcted myocardium with high engraf...
This project developed a mechanical model for simulating blood flow through the abdominal aorta and ...
The goal of this project was to study the effect of low vimentin levels on the structure, mechanics,...
Currently there is an urgent clinical need for small diameter vascular grafts. Tissue engineered blo...
Cyclic mechanical loading improves strength and extracellular matrix (ECM) synthesis in tissue engin...
Electronic pacemakers are widely used to treat cardiac pacing problems, but the devices have inheren...
Several studies have shown that human mesenchymal stem cells (hMSCs)have the potential to be the fut...
Currently, infallible cancer treatment has not been achieved. Doxorubicin (DOX), an active anticance...
Severe burn injuries lead to significant morbidity and mortality as they are traumatic and affect ne...
Pressure ulcers occur when the tissue has capillary occlusion leading to necrosis and ultimately an ...
It is difficult to predict the toxic effects of pesticides on humans because traditional 2D cell cul...
Electrodialysis (ED) is an established technology used to transport small ions from one solution to ...
It is thought that stem cells hold promise for use in future therapeutics. One such application is ...