Huperzine A and B, alkaloids isolated from the club moss Huperzia serrata, are employed in traditional Chinese medicine to treat senile dementia and other ailments. Previous attempts to synthesize Huperzine analogs relying on a heteroatom directed photoarylation reaction encountered difficulties when a pyridine ring system was incorporated into the photoprecursor. This research seeks to develop an alternative to photochemical initiation of the heteroatom directed arylation employing microwave radiation
The field of synthesis of organic compounds having medicinal importance is in a state of boom develo...
Abstract: The impact of genomics and proteomics is additionally creating an explosion in the number ...
AbstractWe disclose a new microwave-assisted protocol for the effective α-arylation of diethyl malon...
In one synthetic route toward analogs of Huperzine, a natural potent reversible inhibitor of acetylc...
The primary goal of this project is to explore the synthesis of huperzine alkaloids via the photoini...
2021 Celebration of Student Research and Creativity presentation"Heteroaryl compounds are important ...
Photocyclization of aryl vinyl ethers reportedly proceeds via carbonyl ylide intermediates. Previous...
Heterocyclic compounds hold a special place among pharmaceutically important natural and synthetic m...
The synthesis of two new Huperzine A analogues is reported. Both products present an amino substitut...
A general method for the synthesis of pyrrolizidine derivatives using an intramolecular hydroaminome...
A novel and convenient microwave-assisted synthesis of an active metabolite (EXP-3174) of losartan i...
We have established an efficient method for the synthesis of the arylpiperazine derivatives in which...
Abstract: Organic compounds not only make up life on earth but a wide variety of classes also have h...
Microwave irradiation has become a popular heating technique in organic synthesis, mainly due to its...
Pyridazines are nitrogen-containing compounds that have been found to show a number of pharmaceutica...
The field of synthesis of organic compounds having medicinal importance is in a state of boom develo...
Abstract: The impact of genomics and proteomics is additionally creating an explosion in the number ...
AbstractWe disclose a new microwave-assisted protocol for the effective α-arylation of diethyl malon...
In one synthetic route toward analogs of Huperzine, a natural potent reversible inhibitor of acetylc...
The primary goal of this project is to explore the synthesis of huperzine alkaloids via the photoini...
2021 Celebration of Student Research and Creativity presentation"Heteroaryl compounds are important ...
Photocyclization of aryl vinyl ethers reportedly proceeds via carbonyl ylide intermediates. Previous...
Heterocyclic compounds hold a special place among pharmaceutically important natural and synthetic m...
The synthesis of two new Huperzine A analogues is reported. Both products present an amino substitut...
A general method for the synthesis of pyrrolizidine derivatives using an intramolecular hydroaminome...
A novel and convenient microwave-assisted synthesis of an active metabolite (EXP-3174) of losartan i...
We have established an efficient method for the synthesis of the arylpiperazine derivatives in which...
Abstract: Organic compounds not only make up life on earth but a wide variety of classes also have h...
Microwave irradiation has become a popular heating technique in organic synthesis, mainly due to its...
Pyridazines are nitrogen-containing compounds that have been found to show a number of pharmaceutica...
The field of synthesis of organic compounds having medicinal importance is in a state of boom develo...
Abstract: The impact of genomics and proteomics is additionally creating an explosion in the number ...
AbstractWe disclose a new microwave-assisted protocol for the effective α-arylation of diethyl malon...