Interaction with the CD4 co-receptor can change tropism in HIV-1. It has been shown that CCR5-using isolates cultured in vitro without the presence of neutralizing antibodies can be more efficient at infection, while at the same time becoming more sensitive to neutralization. This project studies CXCR4-using envelopes examining the effect of viral isolation on tropism, receptor use, and antibody sensitivity. The cultured CXCR4-using isolates did not evolve different properties from the uncultured CXCR4-using isolate
HIV-1 uses specific cell surface receptors to gain entry into host cells. Different strains vary in...
Influenza is a major cause of human illness and death, and as such requires vast attention.Current v...
Includes bibliographical references (leaves 124-150).The female genital tract serves as the major po...
Every year millions of people contract HIV or die from HIV-AIDS related illnesses. Since current dr...
HIV envelop genes specify which types of host cells the virus can infect. HIV clones carrying five ...
The goal of this project was to test Pichinde virus isolates for in vitro and in vivo viability, and...
This project focused on investigating the binding properties of a panel of rabbit monoclonal antibod...
Developing a vaccine against HIV has been very difficult mainly because HIV is highly variable. Many...
Five to ten percent of HIV-1 infected individuals remain asymptomatic up to a year after infection. ...
Human Cytomegalovirus (HCMV) infection can progress into a persistent and life-threatening disease i...
The aim of this study was to compare the magnitude and breadth of HIV-specific T cell responses to H...
In response to a viral antigen, the immune system produces epitope-specific T-cells. The majority be...
In this work a new approach to determine the co-receptor tropism of HIV patients is presented and ev...
The ability of HIV-1 to interact with receptors on the host cell plays a major role in determining i...
Includes abstract.Includes bibliographical references.Immunization against vaccine-preventable infec...
HIV-1 uses specific cell surface receptors to gain entry into host cells. Different strains vary in...
Influenza is a major cause of human illness and death, and as such requires vast attention.Current v...
Includes bibliographical references (leaves 124-150).The female genital tract serves as the major po...
Every year millions of people contract HIV or die from HIV-AIDS related illnesses. Since current dr...
HIV envelop genes specify which types of host cells the virus can infect. HIV clones carrying five ...
The goal of this project was to test Pichinde virus isolates for in vitro and in vivo viability, and...
This project focused on investigating the binding properties of a panel of rabbit monoclonal antibod...
Developing a vaccine against HIV has been very difficult mainly because HIV is highly variable. Many...
Five to ten percent of HIV-1 infected individuals remain asymptomatic up to a year after infection. ...
Human Cytomegalovirus (HCMV) infection can progress into a persistent and life-threatening disease i...
The aim of this study was to compare the magnitude and breadth of HIV-specific T cell responses to H...
In response to a viral antigen, the immune system produces epitope-specific T-cells. The majority be...
In this work a new approach to determine the co-receptor tropism of HIV patients is presented and ev...
The ability of HIV-1 to interact with receptors on the host cell plays a major role in determining i...
Includes abstract.Includes bibliographical references.Immunization against vaccine-preventable infec...
HIV-1 uses specific cell surface receptors to gain entry into host cells. Different strains vary in...
Influenza is a major cause of human illness and death, and as such requires vast attention.Current v...
Includes bibliographical references (leaves 124-150).The female genital tract serves as the major po...