Introduction: Molecular characterisation of the breast cancer has allowed for targeted therapies that are improving outcomes. The gains achieved by these treatments have fuelled the search for other targets, including cyclin-dependent kinase inhibitors such as p21. p21 expression in breast cancer has been shown to be variably associated with clinical and pathological parameters in different populations. It is possible that either methodological or biological differences underlie these variations. Objective: The current study sought to determine the association of p21 expression and clinico-pathological parameters in breast cancer patients at the Aga Khan University Hospital in Nairobi, Kenya. Methods: Clinically annotated tissue samples wer...
Background: Cancer of the breast is the most common organ-specific cancer, affecting women worldwide...
The differential expression of the ras oncogene product p21 in the primary tumor, regional nodes, an...
Contains fulltext : 57604.pdf (publisher's version ) (Closed access)Breast cancer ...
Introduction: Molecular characterisation of the breast cancer has allowed for targeted therapies tha...
Background and Aim: The mutation in the wild-type tumor suppressor gene p53 is the most common genet...
Background: Cervical cancer is one of the leading causes of female mortality worldwide. About 85% oc...
p21 protein (p21) inhibitor of cyclin-dependent kinases is a critical downstream effector in the p53...
[[abstract]]Purpose: The diversity of biological functions makes p21Cip1/WAF1 (p21) a controversial ...
Purpose: The diversity of biological functions makes p21(Cip 1/WAF1) (p21 ) a controversial marker i...
Introduction: Cytokeratin fragment 21.1 (CYFRA 21.1) assay detects a serum fragment of cytokeratin 1...
grantor: University of Torontop21/WAF1/CIP1/SDI1 is a putative tumour suppressor gene whic...
An immunocytochemical assay for the p53-regulated protein product of the WAF1/Cip1 gene, p21WAF1 (p2...
Background: Male breast cancer (MBC) is an uncommon disease, and most of our current knowledge of it...
Purpose: In vitro, p21-activated kinase 1 (Pak1) phosphorylates the serine 305 residue of the estrog...
Breast cancer is an increasingly important cause of illness and death among women. In recent years s...
Background: Cancer of the breast is the most common organ-specific cancer, affecting women worldwide...
The differential expression of the ras oncogene product p21 in the primary tumor, regional nodes, an...
Contains fulltext : 57604.pdf (publisher's version ) (Closed access)Breast cancer ...
Introduction: Molecular characterisation of the breast cancer has allowed for targeted therapies tha...
Background and Aim: The mutation in the wild-type tumor suppressor gene p53 is the most common genet...
Background: Cervical cancer is one of the leading causes of female mortality worldwide. About 85% oc...
p21 protein (p21) inhibitor of cyclin-dependent kinases is a critical downstream effector in the p53...
[[abstract]]Purpose: The diversity of biological functions makes p21Cip1/WAF1 (p21) a controversial ...
Purpose: The diversity of biological functions makes p21(Cip 1/WAF1) (p21 ) a controversial marker i...
Introduction: Cytokeratin fragment 21.1 (CYFRA 21.1) assay detects a serum fragment of cytokeratin 1...
grantor: University of Torontop21/WAF1/CIP1/SDI1 is a putative tumour suppressor gene whic...
An immunocytochemical assay for the p53-regulated protein product of the WAF1/Cip1 gene, p21WAF1 (p2...
Background: Male breast cancer (MBC) is an uncommon disease, and most of our current knowledge of it...
Purpose: In vitro, p21-activated kinase 1 (Pak1) phosphorylates the serine 305 residue of the estrog...
Breast cancer is an increasingly important cause of illness and death among women. In recent years s...
Background: Cancer of the breast is the most common organ-specific cancer, affecting women worldwide...
The differential expression of the ras oncogene product p21 in the primary tumor, regional nodes, an...
Contains fulltext : 57604.pdf (publisher's version ) (Closed access)Breast cancer ...