Introduction. Radical pelvic surgery is a major cause of erectile dysfunction due to iatrogenic cavernous nerve damage. Endothelial nitric oxide synthase, which generates nitric oxide (NO) in the cavernosal tissues, localizes to specialized plasma membrane invaginations known as caveolae. Growing evidence suggests that caveolae are major components of signal trafficking and that stimuli that affect the concentration of the main structural protein of caveolae, caveolin-1 influence NO signaling. Aim. To evaluate caveolin-1 expression as a marker of cavernous tissue damage and determine the impact of early sildenafil administration on caveolin-1 expression in animal models of partial and total surgical penile denervation. Methods. Thirty-six r...
After pelvic surgeries such as radical prostatectomy, two major complications - urinary incontinence...
The paracrine effect is the major mechanism of stem cell therapy. However, the details of the effect...
© 2022 American Society of Andrology and European Academy of AndrologyBackground: The main pathophys...
Caveolin-1-deficient mice are characterised by a high vascular NO production. Because NO-dependent s...
Erectile dysfunction is a common complication for patients undergoing surgeries for prostate, bladde...
BackgroundThe pathophysiology of increased severity of erectile dysfunction in men with diabetes and...
Neurogenic impotence is a clinical situation commonly resulting from major pelvic surgery. A detaile...
<div><p>We performed this study to evaluate the effect of cavernous nerve (CN) traction on erectile ...
We performed this study to evaluate the effect of cavernous nerve (CN) traction on erectile function...
OBJECTIVE To examine the effect of pioglitazone on erectile function in a rat model of postprostatec...
The commonly utilized phosphodiesterase type 5 inhibitors do not lead to satisfactory penile erectio...
Aims: Nitric oxide (NO) and hydrogen sulfide (H2S) are involved in nerve-mediated corpus cavernosum ...
Introduction—Neuronal nitric oxide synthase (NOS-I) is significantly decreased with Cavernous Nerve ...
Bilateral cavernous nerve injury results in up-regulation of ROCK signaling in the penis. This is li...
To investigate whether fluorochrome-conjugated phalloidin can delineate cavernous smooth muscle (CSM...
After pelvic surgeries such as radical prostatectomy, two major complications - urinary incontinence...
The paracrine effect is the major mechanism of stem cell therapy. However, the details of the effect...
© 2022 American Society of Andrology and European Academy of AndrologyBackground: The main pathophys...
Caveolin-1-deficient mice are characterised by a high vascular NO production. Because NO-dependent s...
Erectile dysfunction is a common complication for patients undergoing surgeries for prostate, bladde...
BackgroundThe pathophysiology of increased severity of erectile dysfunction in men with diabetes and...
Neurogenic impotence is a clinical situation commonly resulting from major pelvic surgery. A detaile...
<div><p>We performed this study to evaluate the effect of cavernous nerve (CN) traction on erectile ...
We performed this study to evaluate the effect of cavernous nerve (CN) traction on erectile function...
OBJECTIVE To examine the effect of pioglitazone on erectile function in a rat model of postprostatec...
The commonly utilized phosphodiesterase type 5 inhibitors do not lead to satisfactory penile erectio...
Aims: Nitric oxide (NO) and hydrogen sulfide (H2S) are involved in nerve-mediated corpus cavernosum ...
Introduction—Neuronal nitric oxide synthase (NOS-I) is significantly decreased with Cavernous Nerve ...
Bilateral cavernous nerve injury results in up-regulation of ROCK signaling in the penis. This is li...
To investigate whether fluorochrome-conjugated phalloidin can delineate cavernous smooth muscle (CSM...
After pelvic surgeries such as radical prostatectomy, two major complications - urinary incontinence...
The paracrine effect is the major mechanism of stem cell therapy. However, the details of the effect...
© 2022 American Society of Andrology and European Academy of AndrologyBackground: The main pathophys...