Liu et al. (2018) report a mathematical model predicting how the cellular repertoire of SCF E3 ligases is assembled by “adaptive exchange on demand,” with the limited pool of CUL1 scanning the vast sea of F-box proteins for those with substrates demanding ubiquitylation
Funder: Max-Planck-Gesellschaft; FundRef: http://dx.doi.org/10.13039/501100004189Funder: Canada Rese...
SummaryThe modular SCF (Skp1, cullin, and F box) ubiquitin ligases feature a large family of F box p...
AbstractThe SCF (Skp1–Cullin–F-box) E3 ubiquitin ligase family was discovered through genetic requir...
The modular SCF (Skp1, cullin, and F box) ubiquitin ligases feature a large family of F box protein ...
The modular SCF (Skp1, cullin, and F box) ubiquitin ligases feature a large family of F box protein ...
SummaryThe modular SCF (Skp1, cullin, and F box) ubiquitin ligases feature a large family of F box p...
SCF (Skp1-Cullin-F-box) ubiquitin ligases comprise several dozen modular enzymes that have diverse r...
The cullin-RING ligases (CRLs) form the major family of E3 ubiquitin ligases. The prototypic CRLs in...
The cullin-RING ligases (CRLs) form the major family of E3 ubiquitin ligases. The prototypic CRLs in...
The human genome encodes 69 different F-box proteins (FBPs), each of which can potentially assemble ...
The human genome encodes 69 different F-box proteins (FBPs), each of which can potentially assemble ...
Cullin-RING ubiquitin ligases (CRLs) catalyze the ubiquitylation of substrates many of which are deg...
The cullin-RING ligases (CRLs) form the major family of E3 ubiquitin ligases. The prototypic CRLs in...
The cullin-RING ligases (CRLs) form the major family of E3 ubiquitin ligases. The prototypic CRLs in...
E3 ligases are typically classified by hallmark domains such as RING and RBR, which are thought to s...
Funder: Max-Planck-Gesellschaft; FundRef: http://dx.doi.org/10.13039/501100004189Funder: Canada Rese...
SummaryThe modular SCF (Skp1, cullin, and F box) ubiquitin ligases feature a large family of F box p...
AbstractThe SCF (Skp1–Cullin–F-box) E3 ubiquitin ligase family was discovered through genetic requir...
The modular SCF (Skp1, cullin, and F box) ubiquitin ligases feature a large family of F box protein ...
The modular SCF (Skp1, cullin, and F box) ubiquitin ligases feature a large family of F box protein ...
SummaryThe modular SCF (Skp1, cullin, and F box) ubiquitin ligases feature a large family of F box p...
SCF (Skp1-Cullin-F-box) ubiquitin ligases comprise several dozen modular enzymes that have diverse r...
The cullin-RING ligases (CRLs) form the major family of E3 ubiquitin ligases. The prototypic CRLs in...
The cullin-RING ligases (CRLs) form the major family of E3 ubiquitin ligases. The prototypic CRLs in...
The human genome encodes 69 different F-box proteins (FBPs), each of which can potentially assemble ...
The human genome encodes 69 different F-box proteins (FBPs), each of which can potentially assemble ...
Cullin-RING ubiquitin ligases (CRLs) catalyze the ubiquitylation of substrates many of which are deg...
The cullin-RING ligases (CRLs) form the major family of E3 ubiquitin ligases. The prototypic CRLs in...
The cullin-RING ligases (CRLs) form the major family of E3 ubiquitin ligases. The prototypic CRLs in...
E3 ligases are typically classified by hallmark domains such as RING and RBR, which are thought to s...
Funder: Max-Planck-Gesellschaft; FundRef: http://dx.doi.org/10.13039/501100004189Funder: Canada Rese...
SummaryThe modular SCF (Skp1, cullin, and F box) ubiquitin ligases feature a large family of F box p...
AbstractThe SCF (Skp1–Cullin–F-box) E3 ubiquitin ligase family was discovered through genetic requir...
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