Expression of Fcγ receptors type II (FcγRII) in chronic lymphocytic leukemia B cells [4]
- Gamberale, Romina
- Geffner, Jorge Raúl
- Sanjurjo, Julieta
- Fernandez Calloti, Paula X.
- Arrosagaray, Guillermo
- Sánchez Ávalos, Julio César Américo
- Giordano, Mirta Nilda
DOIAbstract
We have read with interest the paper from Damle et al analyzing the surface membrane phenotype of B lymphocytes in chronic lymphocytic leukemia (B-CLL). The authors stated that the leukemic cells from all B-CLL patients evaluated (irrespective of immunoglobulin heavy chain (IgVH) gene mutational status) bear the phenotype of antigen-experienced B cells based, among other features, on the very low expression of Fcγ receptors type IIb (FcγRIIb, CD32), which is the main isoform of FcγRII in B lymphocytes.Fil: Gamberale, Romina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; ArgentinaFil: Geffner, Jorge Raúl. Conse...
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