Urinary steroid profiling in women hints at a diagnostic signature of the polycystic ovary syndrome: A pilot study considering neglected steroid metabolites
- Dhayat, Nasser A
- Marti, Nesa
- Kollmann, Zahraa
- Troendle, Amineh
- Bally, Lia
- Escher, Geneviève
- Grössl, Michael
- Ackermann, Daniel
- Ponte, Belen
- Pruijm, Menno
- Müller, Michael
- Vogt, Bruno
- Birkhäuser, Martin H
- Bochud, Murielle
- Flück, Christa E
Publication date
January 2018
DOI Publisher
Public Library of Science (PLoS)Abstract
Although the polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women with vast metabolic consequences, its etiology remains unknown and its diagnosis is still made by exclusion. This study aimed at characterizing a large number of urinary steroid hormone metabolites and enzyme activities in women with and without PCOS in order to test their value for diagnosing PCOS
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