Prévenir la coqueluche chez le nouveau-né : mère vaccinée durant la grossesse, nourrisson protégé

Pertussis is a serious health issue in infants < 3 months. Too young to be vaccinated, they are at higher risk of developing pertussis and vulnerable to severe complications. Two vaccine strategies exist to prevent infant pertussis. The older « cocooning » strategy involves vaccinating parents and close contacts, indirectly protecting newborns. The more effective strategy is to immunize women during pregnancy, providing infants passive protection by transplacental transfer of pertussis antibodies. However, some women and their caregivers are worried about receiving the vaccine during pregnancy. We review the effectiveness, safety, timing and implementation of pertussis antenatal immunization. The aim is to remind practitioners of current recommendations with supporting data. This can be used to reassure future parents and enable informed decisions