Commonly referred as autophagy, macroautophagy is one of the major degradative pathways in eukaryotic cells. During macroautophagy, cytosolic material is engulfed in the autophagosome, a double-membrane-bound vesicle. The autophagosome fuses with endo-lysosomal vesicles, leading to degradation and recycling of the sequestered substrates.Autophagy has been recently shown to play a role in the innate and adaptive immune responses, by acting at multiple and diverse levels. In particular, our group has recently shown that autophagy promotes MHC Class I internalization and degradation in murine dendritic Cells (DCs). Human Leukocyte Antigen-B27 (HLA-B2) is strongly associated with the onset of ankylosing spondylitis, an inflammatory rheumatholog...
Autophagy describes catabolic pathways that deliver cytoplasmic constituents for lysosomal degradati...
© 2017 Elsevier Ltd Autophagy is a ubiquitous cellular mechanism for the targeted lysosomal degradat...
Autophagy is a process of lysosomal degradation that was originally described as a cellular response...
Autophagy (or macroautophagy) is an evolutionarily conserved lysosomal degradation pathway in eukary...
Autophagy is a lysosomal degradation mechanism in eukaryotic organisms and has a crucial role in cel...
Autophagy is an intracellular homeostatic mechanism important for the degradation of waste component...
Autophagy is an intracellular homeostatic mechanism important for the degradation of waste component...
Autophagy is a physiological cellular mechanism that degrades and recycles proteins and other molecu...
Autophagy is a physiological cellular mechanism that degrades and recycles proteins and other molecu...
In its classical form, autophagy is a pathway by which cytoplasmic constituents, including intracell...
Autophagy is an essential, homeostatic process by which cells break down their own components. Perha...
Macroautophagy was originally discovered as a nutrient salvage pathway during starvation. By now it ...
© 2014 Natalie Louise PattersonAutophagy is an evolutionary conserved pathway of protein degradation...
Autophagy is a group of cellular pathways that deliver cytoplasmic constituents for lysosomal degrad...
Autophagy is considered as an important intracellular mechanism that degrades cytoplasmic components...
Autophagy describes catabolic pathways that deliver cytoplasmic constituents for lysosomal degradati...
© 2017 Elsevier Ltd Autophagy is a ubiquitous cellular mechanism for the targeted lysosomal degradat...
Autophagy is a process of lysosomal degradation that was originally described as a cellular response...
Autophagy (or macroautophagy) is an evolutionarily conserved lysosomal degradation pathway in eukary...
Autophagy is a lysosomal degradation mechanism in eukaryotic organisms and has a crucial role in cel...
Autophagy is an intracellular homeostatic mechanism important for the degradation of waste component...
Autophagy is an intracellular homeostatic mechanism important for the degradation of waste component...
Autophagy is a physiological cellular mechanism that degrades and recycles proteins and other molecu...
Autophagy is a physiological cellular mechanism that degrades and recycles proteins and other molecu...
In its classical form, autophagy is a pathway by which cytoplasmic constituents, including intracell...
Autophagy is an essential, homeostatic process by which cells break down their own components. Perha...
Macroautophagy was originally discovered as a nutrient salvage pathway during starvation. By now it ...
© 2014 Natalie Louise PattersonAutophagy is an evolutionary conserved pathway of protein degradation...
Autophagy is a group of cellular pathways that deliver cytoplasmic constituents for lysosomal degrad...
Autophagy is considered as an important intracellular mechanism that degrades cytoplasmic components...
Autophagy describes catabolic pathways that deliver cytoplasmic constituents for lysosomal degradati...
© 2017 Elsevier Ltd Autophagy is a ubiquitous cellular mechanism for the targeted lysosomal degradat...
Autophagy is a process of lysosomal degradation that was originally described as a cellular response...