ASSESMENT OF NUTRITIONAL STATUS OF PATINETS THAT BEGAN SYSTEMIC THERAPY OF COLORECTAL CANCER AT THE UNIVERSITY HOSPITAL FOR TUMORS

Uvod: Pretilost, izražena indeksom tjelesne mase (BMI „body mass index“) većim od 30 kg/m2, utvrđeni je čimbenik rizika za razvoj raka debelog crijeva. Nenamjerni gubitak na tjelesnoj masi jedan je od simptoma raka debelog crijeva i neprepoznat može dovesti do kaheksije, povezane s lošijim ishodom sustavne antineoplastične terapije i lošijom kvalitetom života bolesnika. Cilj: Cilj ovog rada je procijeniti nutritivni status oboljelih od raka debelog crijeva liječenih u Odjelu internističke onkologije Klinike za tumore služeći se upitnikom procjene nutritivnog rizika NRS 2002. Metode: Retrospektivno smo analizirali nutritivni status 175 bolesnika koji su od svibnja 2016. do svibnja 2018. započeli sustavno antineoplastično liječenje raka debelog crijeva u Odjelu internističke onkologije Klinike za tumore. Nizak nutritivni rizik definiran je rezultatom 0-2, a visoki nutritivni rizik definiran je rezultatom 3 ili više. U analizu je bilo uključno 106 muškaraca i 71 žena, prosječne životne dobi 62 godine. Rezultati: Većina bolesnika koji su započeli sustavno liječenje raka debelog crijeva u analiziranom razdoblju bila je niskog nutritivog rizika, 122 (70%) bolesnika. Visok nutritivni rizik opažen je u 53 (30%) bolesnika, u 11 (37%) bolesnika liječenih zbog ranog raka debelog crijeva i 42 (29%) bolesnika liječenih zbog proširenog raka debelog crijeva. Većina bolesnika bila je prekomjernog indeksa tjelesne mase (BMI > 25 kg/m2) i u toj skupini bolesnika, visok nutritivni rizik opažen je u ¼ bolesnika (27 (26%) bolesnika). Zaključak: Procjena nutritivnog statusa bolesnika oboljelih od raka debelog crijeva odgovarajućim alatima, trebala bi biti dio svakodnevne liječničke prakse kako bi se bolesnicima osigurala odgovarajuća potporna skrb te poboljšao ishod liječenja i preživljenje oboljelih od raka debelog crijeva.Introduction: Obesity, measured by body mass index (BMI) of 30 kg/m2 or more, is etablished risk factor for the development of colorectal cancer. Unintetional body weight loss is one of the symptoms of colorectal cancer and unrecognised may lead to cachexia, associated with a poor outcomes of systemic antineoplastic therapy and patients poor quality of life. Aim: The aim of this paper is to evaluate nutritional status of patients that began systemic therapy of colorectal cancer at the Department of Oncology, University Hospital for Tumors using the nutritional screening tool NRS 2002. Methods: Retrospectivley we analysed nutritional status of 175 patients that began systemic therapy of colorectal cancer from May 2016 until May 2018. Low nutritional risk was defined as NRS 2002 score of 0-2 and high nutritional risk as NRS 2002 score of 3 or more. There were 106 men and 71 women, median age of 62 years. Results: Majority of patients that began systemic therapy of colorectal cancer in analyzed period had low nutritional risk, 122 (70%) patients. High nutritional risk was observed in 53 (30%) patients, in 11 (37%) patients with early colorectal cancer and 42 (29%) patients with metastatic colorectal cancer. Majority of patients were overweight (BMI > 25 kg/m2) and in ¼ of these patients (27 (26%) patients) high nutritional risk was observed. Conclusion: Assesment of nutritional status of colorectal cancer patients using appropriate nutritional screening tool should be implement in medical practice in order to provide adequate supportive care and therefore improve therapeutic and survival outcomes of colorectal cancer patients