Patohistološki standardi za karcinom dojke

Diagnosis and treatment of breast cancer has progressed rapidly in recent 20 years. The diagnosis was fi rst based on clinical appearance that changes after the introduction of mammography in the diagnosis. Development of radiological techniques has led to the detection of a small and non-palpable lesions, and surgeons are increasingly applied conserving procedures for breast cancer. Therefore, today is a very important multidisciplinary team in the treatmentof patients with breast cancer. A pathologist is a key member of the multidisciplinary team who determines the prognostic and predictive factors for patients with breast cancer which require some standardized protocols and processing of tissue samples.Dijagnostika i liječenje karcinoma dojke je posljednjih 20 godina vrlo brzo napredovalo. U prvo vrijeme dijagnoza se postavljala na temelju kliničkih nalaza što se promijenilo uvođenjem mamografije. Razvoj radioloških metoda doveo je do otkrivanja malih i nepalpabilnih lezija te su kirurzi počeli primjenjivati poštedne kirurške zahvate nakon kojih slijedi adjuvantno liječenje. Zbog toga je danas vrlo važan multidisciplinarni tim u liječenju bolesnica s karcinomom dojke. Patolog je ključni član multidisciplinarnog tima jer mora odrediti brojne prognostičke i prediktivne čimbenike za bolesnice s karcinomom dojke što sve zahtjeva odgovarajuće standardizirane protokole i postupke za uzorke tkiva