Polimorfizam gena OLR1 i funkcionalna svojstva mliječnih krava

The study analyzed the polymorphism of single nucleotide substitution A8232C, located in the 3’UTR region of the receptor of the oxidized low-density lipoprotein (OLR1) gene. The study was conducted in a herd of Polish Holstein-Friesian (Red-and-White strain) dairy cattle. Identification of genotypes of individuals was performed using PCR-RFLP. The study stated the following frequency of A8232C polymorphism alleles: A - 0.30 and C - 0.70. Statistical analysis showed that the AC genotype cows were characterized by higher milk yield, protein and fat and for fat yield, the difference was confirmed statistically (P≤0.05). The cows with genotype AA were characterized by the latest occurrence of first calving and the longest intercalving interval, but the results were not confirmed statistically.Analiziran je polimorfizam pojedinačnog nukleotida na poziciji A8232C, smještenog u regiji 3’UTR, gena za receptor oksidiranog lipoproteina male gustoće (OLR1). U stadu poljskih holštajnsko-frizijskih (crveni i bijeli soj) krava za mlijeko genotipovi jedinki identificirani su PCR-RFLP metodom. Ustanovljena je sljedeća učestalost A8232 polimorfnih alela: A - 0,30 i C - 0,70. Statistička je analiza pokazala da su krave s genotipom AC imale veću proizvodnju mlijeka, bjelančevina i masti, pri čemu je razlika za mast potvrđena kao signifikantna (P≤0,05). Krave s genotipom AA imale su kasno prvo teljenje i dugo međutelidbeno razdoblje, no ti rezultati nisu potvrđeni kao statistički signifikantni