Rat Liver Glycogen Structure as a Function of Glycogen Level

The average chain length of glycogen and the incorporation rate of radioactive glucose into it were measured during its accumulation in rat liver. Increasing levels of glycogen in liver were produced by various treatments of rats. The measured parametres increase with the increase in the liver glycogen content until this reaches the concentration of approximately 2.50/o and then remain more or less constant. At this •stage of glycogen accumulation in rat liver an agglomeration of glycogen subparticles seems to take place. It is concluded that the rat liver glycogen structure is related only to glycogen concentration and is not influenced specificaHy by the agents which affect glycogen level