The dog can spontaneously develop prostate cancer and consequently can be used as an experimental model for prostatic diseases associated with aging, including benign prostate hyperplasia (BPH) and prostate carcinoma (PCa). DNA copy number variations (CNVs) have been used to identify genes associated with cancer development and progression. DNA microarray based comparative genomic hybridization (aCGH) is a technique that allows to identify copy number of thousands of genes throughout the genome. aCGH was used to identify genomic regions with significantly different DNA copy number in three benign prostatic hyperplasia (BPH), four proliferative inflammatory atrophy (PIA), and 14 canine prostate carcinoma (PCa). Five histologically normal pro...
Background: Copy number aberrations frequently occur during the development of many cancers. Such ev...
Prostate cancer is the most common male cancer in Western countries. The genetic mechanism underlyin...
The canine genome offers a wide field for genetic studies on various areas like e.g. phenotypic dive...
The canis lupus familiares is the only species besides human that spontaneously develop prostatic ca...
Recognition of the domestic dog as a model for the comparative study of human genetic traits has led...
BACKGROUND. Prostate cancer is a common disease among men but the knowledge of the Prostate carcinog...
Human and dogs share several similarities in their prostate disorders. The dog has therefore been pr...
Prostate cancer (PCa) in dogs is a highly malignant disease akin to its human counterpart. In contra...
Akin to the situation in humans, dogs are frequently affected by tumors of the prostate. The maligna...
Identification of target genes for genetic rearrangements in prostate cancer and the impact of copy ...
AbstractIdentification of target genes for genetic rearrangements in prostate cancer and the impact ...
Identification of target genes for genetic rearrangements in prostate cancer and the impact of copy ...
Mammary tumors are the most frequent cancers in female dogs exhibiting a variety of histopathologica...
The sequencing of the canine genome, combined with additional genomic technologies, has created oppo...
The dog is one of the few species to develop spontaneous prostate carcinoma (PCA) and is thus an att...
Background: Copy number aberrations frequently occur during the development of many cancers. Such ev...
Prostate cancer is the most common male cancer in Western countries. The genetic mechanism underlyin...
The canine genome offers a wide field for genetic studies on various areas like e.g. phenotypic dive...
The canis lupus familiares is the only species besides human that spontaneously develop prostatic ca...
Recognition of the domestic dog as a model for the comparative study of human genetic traits has led...
BACKGROUND. Prostate cancer is a common disease among men but the knowledge of the Prostate carcinog...
Human and dogs share several similarities in their prostate disorders. The dog has therefore been pr...
Prostate cancer (PCa) in dogs is a highly malignant disease akin to its human counterpart. In contra...
Akin to the situation in humans, dogs are frequently affected by tumors of the prostate. The maligna...
Identification of target genes for genetic rearrangements in prostate cancer and the impact of copy ...
AbstractIdentification of target genes for genetic rearrangements in prostate cancer and the impact ...
Identification of target genes for genetic rearrangements in prostate cancer and the impact of copy ...
Mammary tumors are the most frequent cancers in female dogs exhibiting a variety of histopathologica...
The sequencing of the canine genome, combined with additional genomic technologies, has created oppo...
The dog is one of the few species to develop spontaneous prostate carcinoma (PCA) and is thus an att...
Background: Copy number aberrations frequently occur during the development of many cancers. Such ev...
Prostate cancer is the most common male cancer in Western countries. The genetic mechanism underlyin...
The canine genome offers a wide field for genetic studies on various areas like e.g. phenotypic dive...