Detection of Mayaro virus infections during a dengue outbreak in Mato Grosso, Brazil

Vieira, Carla Julia da Silva Pessoa
Silva, David José Ferreira da
Barreto, Eriana Serpa
Siqueira, Carlos Eduardo Hassegawa
Colombo, Tatiana Elias
Ozanic, Katia
Schmidt, Diane Johnson
Drumond, Betania Paiva
Mondini, Adriano
Nogueira, Mauricio Lacerda
Bronzoni, Roberta Vieira de Morais

Open link

Publication date

July 2015

DOI

10.1016/j.actatropica.2015.03.020

Publisher

Elsevier B.V.

Journal

issn:0001-706X

Abstract

Arboviruses are common agents of human febrile illness worldwide. In dengue-endemic areas illness due to other arboviruses have been misdiagnosed as dengue based only on clinical-epidemiological data. In this study we investigated the presence of Brazilian arboviruses in sera of 200 patients presenting acute febrile illness, during a dengue outbreak in Sinop, MT, Brazil. The results showed that 38 samples were positive to Dengue virus (DENV) type 1, two samples to DENV type 4, and six to Mayaro virus. These results indicate that arboviruses others than DENV are circulating in Sinop and the surrounding region, which are going undiagnosed. In addition, molecular and evolutionary analyses indicate that two MAYV genotypes are co-circulating in ...