Expression pattern of \(\it Axin2\) during chicken development

Canonical \(\it Wnt\)-signalling is well understood and has been extensively described in many developmental processes. The regulation of this signaling pathway is of outstanding relevance for proper development of the vertebrate and invertebrate embryo. \(\it Axin2\) provides a negative-feedback-loop in the canonical \(\it Wnt\)-pathway, being a target gene and a negative regulator. Here we provide a detailed analysis of the expression pattern in the development of the chicken embryo. By performing \(\textit {in-situ}\) hybridization on chicken embryos from stage HH 04+ to HH 32 we detected a temporally and spatially restricted dynamic expression of \(\it Axin2\). In particular, data about the expression of \(\it Axin2\) mRNA in early embryogenesis, somites, neural tube, limbs, kidney and eyes was obtained