MANAGEMENT AND PROGNOSTIC FACTORS OF SQUAMOUS CELL CARCINOMA AND ADENOCARCINOMA OF THE UTERINE CERVIX

To investigate the clinicopathological characteristics and survival of squamous cell carcinoma and adenocarcinoma the cervix using Surveillance, Epidemiology, and End Results database. Patients with a diagnosis of squamous cell carcinoma and adenocarcinoma of the cervix were included between 2014 and 2019. Kaplan-Meier method and Cox regression models were used. A total of 189 patients were included. Of the patients with known International Federation of Gynecology and Obstetrics stage and tumor grade, the stage III disease was diagnosed in 42.78% patients, and 26.46.5% patients had poorly or undifferentiated histology and well differentiated are 67.72%. The 5-year cause specific survival and overall survival were 33.0% and 29.4%, respectively. In multivariate analysis, increasing age, advanced stage, and treatment by primary radiotherapy were associated with worse survival outcomes. Squamous cell carcinoma and adenocarcinoma of the cervix are rare diseases with aggressive characteristics and prone to metastasize and is dismal in prognosis. Reduced survival was associated with increasing age, advanced stage, and treatment by primary radiotherapy [1] [3]