Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer
- Phelan, Catherine M.
- Kuchenbaecker, Karoline B.
- Tyrer, Jonathan P.
- Kar, Siddhartha P.
- Lawrenson, Kate
- Winham, Stacey J.
- Dennis, Joe
- Pirie, Ailith
- Riggan, Marjorie
- Chornokur, Ganna
- Earp, Madalene A.
- Leroux, Dominique
- Spurdle, Amanda B.
- Jensen, Allan
- Tworoger, Shelley S.
- Wu, Xifeng
- Hodgson, Shirley
- Thomsen, Liv Cecilie Vestrheim
- Chiew, Yoke-Eng
- Caligo, Maria A.
- Tihomirova, Laima
- Garcia, Maria Jose
- Prieur, Fabienne
- Levine, Douglas A.
- Swerdlow, Anthony J.
- Friebel, Tara M.
- Peixoto, Ana
- Moysich, Kirsten B.
- Conner, Thomas
- Sieh, Weiva
- Banerjee, Susana N.
- Mendoza-Fandino, Gustavo A.
- Olswold, Curtis
- Lele, Shashikant B.
- Thull, Darcy L.
- Antonenkova, Natalia N.
- Ferrer, Sandra Fert
- Lee, Andrew
- Soucy, Penny
- Black, Amanda
- Khusnutdinova, Elza
- Leslie, Goska
- Paul, James
- Domchek, Susan M.
- van ensburg, Elizabeth J.
- Heetvelde, Mattias Van
- Bradbury, Angela R.
- Kim, Sung-Won
- Azzollini, Jacopo
- Poppe, Bruce
- Menon, Usha
- Ness, Roberta B.
- May, Taymaa
- Prokofyeva, Darya
- Pugh, Elizabeth
- Buecher, Bruno
- Ding, Yuan Chun
- Goldgar, David E.
- Ong, Kai Ren
- Dork, Thilo
- Giles, Graham G.
- Hulick, Peter J.
- Lázaro García, Conxi
- Szafron, Lukasz
- Brewer, Carole
- Southey, Melissa C.
- Hein, Alexander
- Ellis, Steve
- Hildebrandt, Mat
- Study EMBRACE
- Glasspool, Rosalind
- Peissel, Bernard
- Monteiro, Alvaro N.
- Onland-Moret, N. Charlotte
- Piskorz, Anna M.
- Neuhausen, Susan L.
- Chanock, Stephen J.
- Rothstein, Joseph H.
- Sandler, Dale P.
- Pujana Genestar, M. Ángel
- Dao, Fanny
- Bean, Yukie
- Godwin, Andrew K.
- Webb, Penelope M.
- Richardson, Andrea
- Kjaer, Susanne Krüger
- Hahnen, Eric
- Pezzani, Lidia
- Nedergaard, Lotte
- Kwong, Ava
- Hooning, Maartje J.
- Merritt, Melissa A.
- Cook, Linda S.
- Risch, Harvey A.
- Palli, Domenico
- Meijers-Heijboer, Hanne
- Coetzee, Simon
- Lambrechts, Diether
- Zorn, Kristin K.
- Salvesen, Helga B.
- Piedmonte, Marion
- Pedersen, Inge Søkilde
- Odunsi, Kunle
- Antoniou, Antonis C.
- Cescon, Terence
- Meindl, Alfons
- Offit, Kenneth
- Høgdall, Estrid
- Harrington, Patricia A.
- Schmutzler, Rita Katharina
- Trichopoulou, Antonia
- Poblete, Samantha R.
- Amos, Christopher I.
- Le, Nhu D.
- Teixeira, Manuel R.
- Schoemaker, Minouk J.
- Doherty, Jennifer Anne
- Wijnen, Juul
- Foulkes, William D.
- Radice, Paolo
- Phillips, Kelly-Anne
- Simard, Jacques
- Ferguson, Sarah
- Kupryjanczyk, Jolanta
- Eilber, Ursula
- Edwards, Todd
- Huzarski, Tomasz
- Orsulic, Sandra
- Lyra, Paulo C.
- Szabo, Csilla I.
- Blankstein, Kenneth
- Bjorge, Line
- Beesley, Jonathan
- Papi, Laura
- Fortner, Renée T.
- Trabert, Britton
- Romm, Jane
- Shelford, Tameka
- Rennert, Gad
- Tung, Nadine
- Håkansson, Niclas
- Janavicius, Ramunas
- Lissowska, Jolanta
- Steinemann, Doris
- Jensen, Uffe Birk
- Liang, Dong
- Karnezis, Anthony N.
- Permuth, Jennifer B.
- Campbell, Ian
- Gore, Martin
- Butzow, Ralf
- Kiemeney, Lambertus A. L. M.
- McNeish, Iain
- Gerdes, Anne-Marie
- Liebrich, Clemens
- Tea, Muy-Kheng
- Edwards, Digna Velez
- Stoppa-Lyonnet, Dominique
- Tognazzo, Silvia
- Siddiqui, Nadeem
- Vratimos, Athanassios
- Wand, Dorothea
- van Altena, Anne M.
- Isaacs, Claudine
- Park-Simon, Tjoung-Won
- Lipworth, Loren
- Brunet, Joan
- Vanderstichele, Adriaan
- Caldes, Trinidad
- Mai, Phuong L.
- Sharma, Priyanka
- Peeters, Petra H. M.
- Mitchell, Gillian
- Anton-Culver, Hoda
- Hosking, Karen
- Daly, Mary B.
- Sutphen, Rebecca
- Rodriguez, Gustavo C.
- Durst, Matthias
- Olopade, Olufunmilayo I.
- Walsh, Christine
- Tinker, Anna V.
- Tan, Yen Y.
- Singer, Christian F.
- Moffitt, Melissa
- Gehrig, Andrea
- Rodriguez Antona, Cristina
- Damirovna, Sakaeva Dina
- Mensenkamp, Arjen R.
- Mazoyer, Sylvie
- Sellers, Thomas A.
- Toland, Amanda Ewart
- Claes, Kathleen B. M.
- Peterlongo, Paolo
- Kelemen, Linda E.
- Wang-Gohrke, Shan
- Jernetz, Mats
- Huntsman, David G.
- Díez Gibert, Orland
- van der Hout, Annemarie H.
- Dansonka-Mieszkowska, Agnieszka
- Kruse, Torben A.
- Lee, Jong Won
- Kennedy, Catherine J.
- Doheny, Kimberly F
- Mulligan, Anna Marie
- Sukiennicki, Grzegorz
- Dossus, Laure
- Schildkraut, Joellen M.
- Henderson, Alex
- Dworniczak, Bernd
- Sutter, Christian
- Lecarpentier, Julie
- Goode, Ellen L.
- Garber, Judy
- Wentzensen, Nicolas
- Barjhoux, Laure
- Gayther, Simon A.
- Manoukian, Siranoush
- Niederacher, Dieter
- Larson, Melissa C.
- Olah, Edith
- Pocza, Timea
- Andrulis, Irene L.
- Terry, Kathryn L.
- Harris, Holly R.
- Lubinski, Jan
- Hamann, Ute
- Osorio, Ana
- Robson, Mark
- Poole, Elizabeth M.
- Park, Sue K.
- Bojesen, Anders
- Ziogas, Argyrios
- Couch, Fergus J.
- Whittemore, Alice
- Brenton, James D.
- Broberg, Per
- Pharoah, Paul D. P.
- Nathanson, Katherine L.
- Porteous, Mary E.
- Haiman, Christopher A.
- Blok, Marinus J.
- McGuffog, Lesley
- Pujol, Pascal
- Weitzel, Jeffrey N.
- Taylor, Jack A.
- Rudolph, Anja
- Fasching, Peter A.
- Modugno, Francesmary
- Narod, Steven A.
- Durán, Mercedes
- Jones, Michael E.
- Song, Honglin
- Brinton, Louise A.
- Hazelett, Dennis
- Ottini, Laura
- Wilkens, Lynne R.
- Arun, Banu K.
- Lester, Jenny
- Dicks, Ed
- Rookus, Matti A.
- Rhiem, Kerstin
- Ganz, Patricia A.
- Berchuck, Andrew
- Holland, Helene
- Thompson, Pamela J.
- Aloisio, Aimee A. D’
- Brooks-Wilson, Angela R.
- Nussbaum, Robert L.
- James, Paul
- Bernardini, Marcus Q.
- Imyanitov, Evgeny N.
- Cannioto, Rikki
- Pfeiler, Georg
- Orr, Nicholas
- Jakubowska, Anna
- Senter, Leigha
- Beckmann, Matthias W.
- John, Esther M.
- McLaughlin, John R.
- Kannisto, Päivi
- Easton, Douglas F.
- Ekici, Arif B.
- Larrañaga, Nerea
- Leminen, Arto
- Aben, Katja K.
- Fountzilas, George
- Yang, Hannah
- Rantala, Johanna
- Pelttari, Liisa M.
- Sobol, Hagay
- Tone, Alicia
- Evans, D. Gareth
- Beeghly-Fadiel, Alicia
- McAlpine, Jessica N.
- Aravantinos, Gerasimos
- Massuger, Leon F. A. G.
- Rossing, Mary Anne
- Adams, Marcia
- Cunningham, Julie M.
- Glendon, Gord
- Chen, Xiao Qing
- Defazio, Anna
- Buys, Saundra S.
- Goranova, Teodora
- Gronwald, Jacek
- Dorfling, Cecilia M.
- Severi, Gianluca
- Travis, Ruth C.
- Vierkant, Robert A.
- Eccles, Diana
- van den Berg, David Berg, David
- Varon-Mateeva, Raymonda
- Goodman, Marc T.
- Barkardottir, Rosa B.
- Kopperud, Reidun K.
- Runnebaum, Ingo B.
- Chiquette, Jocelyne
- Johnatty, Sharon
- Woo, Michelle
- Greene, Mark H.
- Wu, Anna H.
- Cook, Jackie
- Ana, Vega
- Fogarty, Zachary C.
- Pike, Malcolm C.
- Eeles, Rosalind A.
- Gentry-Maharaj, Aleksandra
- van Nieuwenhuysen, Els
- Delnatte, Capucine
- Milne, Roger L.
- Thomassen, Mads
- Hunter, David J.
- Gruber, Stephen B.
- Arver, Brita
- Nevanlinna, Heli
- Vergote, Ignace
- Musinsky, Jacob
- Hauke, Jan
- Ejlertsen, Bent
- Adlard, Julian
- Wappenschmidt, Barbara
- Friedman, Eitan
- Davidson, Rosemarie
- Arnold, Norbert
- O'Malley, David M.
- Chung, Wendy K.
- Barrowdale, Daniel
- Pejovic, Tanja
- Elvira, Mingajeva
- Garcia Barberan, Vanesa
- Chang-Claude, Jenny
- van der Luijt, Rob B.
- Balmaña, Judith
- Wolk, Alicja
- Chenevix-Trench, Georgia
- Kobel, Martin
- Frost, Debra
- Rice, Patricia
- Rappaport-Fuerhauser, Christine
- Vijai, Joseph
- Eng, Kevin H.
- Hung, Jillian
- Lilyquist, Jenna
- Høgdall, Claus K.
- Izatt, Louise
- Hansen, Thomas V. O.
- Lu, Karen H.
- Luccarini, Craig
- Weinberg, Clarice R.
- Benitez, Javier
- Borg, Åke
- Karlan, Beth Y.
- Bermisheva, Marina
- Bodelon, Clara
- Cramer, Daniel W.
- Fridley, Brooke L.
- Pearce, Celeste L.
- Walker, Lisa
- Olsson, Håkan
- Carney, Michael E.
- Aalfs, Cora M.
- Chan, Salina B.
- Huang, Ruea-Yea
- Bogdanova, Natalia V.
- Laitman, Yael
- Tischkowitz, Marc
- Kast, Karin
- Lesueur, Fabienne
- Izquierdo i Font, Àngel Xavier
- Yannoukakos, Drakoulis
- Damiola, Francesca
- Montagna, Marco
- Lundvall, Lene
- Lee, Janet M.
- Side, Lucy E.
- Bonanni, Bernardo
- Setiawan, V. Wendy
- McGuire, Valerie
- Engel, Christoph
- Bruinsma, Fiona
- Marchand, Loïc Le
- Iversen, Edwin S.
- Flanagan, James M.
- Stadler, Zsofia
- Hogervorst, Frans B. L.
- Ramus, Susan J.
- Teo, Soo-Hwang
- Kiiski, Johanna I.
- Hillemanns, Peter
- Birrer, Michael J.
- Fostira, Florentia
- Sucheston-Campbell, Lara E.
- Moes-Sosnowska, Joanna
DOIAbstract
To identify common alleles associated with different histotypes of epithelial ovarian cancer (EOC), we pooled data from multiple genome-wide genotyping projects totaling 25,509 EOC cases and 40,941 controls. We identified nine new susceptibility loci for different EOC histotypes: six for serous EOC histotypes (3q28, 4q32.3, 8q21.11, 10q24.33, 18q11.2 and 22q12.1), two for mucinous EOC (3q22.3 and 9q31.1) and one for endometrioid EOC (5q12.3). We then performed meta-analysis on the results for high-grade serous ovarian cancer with the results from analysis of 31,448 BRCA1 and BRCA2 mutation carriers, including 3,887 mutation carriers with EOC. This identified three additional susceptibility loci at 2q13, 8q24.1 and 12q24.31. Integrated analy...
Add to ORKG