STUDY OF EARLY AND LATE ONSET COMPLICATIONS OF TRANSSPHENOIDAL PITUITARY ADENOMA RESECTION: AN INSTITUITIONAL EXPERIENCE.

Introduction:Considering the unique anatomical location and important role of pituitary gland in regulation of various endocrine functions, various postoperative complications are expected resulting from surgery on pituitary tumor. In this study, we analyzed various complications of transsphenoidal pituitary surgery and factors affecting it. Material and method:Study was conducted between September 2015 to November 2016 on a total of 60 patients. All clinical and surgical data were collected regarding tumor size, symptoms, and residual tumor after surgery, functional remission, symptom relief, and complications. All patients underwent neurological, ophthalmological, and endocrinological examinations before and after resection. Result:Out of 60 patients 43 were operated endoscopically and 17 were operated microscopically. Perioperatively, arachnoid tear was present in 20(33.33%) patients. 23(38.34%) cases were having total resection post-operatively, 20(33.33%) cases were having subtotal resection and in 17 (28.33%) cases either partial resection done or biopsy was taken. Grade of tumor resection was significantly associated with preoperative extent of tumor (p-value-0.003). CSF -leak was associated with Perioperative arachnoid tear significantly (p- value