Background: Radiotherapy is an integral part of breast cancer treatment. Immune activating properties of especially hypofractionated irradiation are in the spotlight of clinicians, besides the well-known effects of radiotherapy on cell cycle and the reduction of the clonogenic potential of tumor cells. Especially combination of radiotherapy with further immune stimulation induces immune-mediated anti-tumor responses. We therefore examined whether hypofractionated irradiation alone or in combination with hyperthermia as immune stimulants is capable of inducing breast cancer cells with immunogenic potential. Methods: Clonogenic assay, AnnexinA5-FITC/Propidium iodide assay and ELISA analyses of heat shock protein 70 and high mobility group box...
It is becoming increasingly evident that radiotherapy may benefit from coincident or subsequent immu...
Recent advancement in the radiotherapy technology has allowed conformal delivery of high doses of io...
Objective: In this study, the hyperthermia effect on the viability of human normal breast (MCF-10A) ...
Background: Radiotherapy is an integral part of breast cancer treatment. Immune activating propertie...
Background Radiotherapy is an integral part of breast cancer treatment. Immune activating propert...
Background: Radiotherapy, administered in fractionated as well as ablative settings, is an essential...
The treatment of breast cancer by radiotherapy can be complemented by hyperthermia. Little is known ...
The major goal of radiotherapy is the induction of tumor cell death. Additionally, radiotherapy can ...
Multimodal tumor treatment settings consisting of radiotherapy and immunomodulating agents such as i...
It is generally accepted that radiotherapy must target clonogenic cells, i.e., those cells in a tumo...
A systemic immune related response (SIME) of radiotherapy has been occasionally observed on metastat...
Objective The goal of this study is to better understand the immunogenetic expression and related cy...
PURPOSE: Hyperthermia (HT) treatment of cancer patients was revived over the last years and has been...
Radiotherapy is an important therapeutic option for the treatment of cancer. Growing evidence indica...
The major goal of radiotherapy is the induction of tumor cell death. Additionally, radiotherapy can ...
It is becoming increasingly evident that radiotherapy may benefit from coincident or subsequent immu...
Recent advancement in the radiotherapy technology has allowed conformal delivery of high doses of io...
Objective: In this study, the hyperthermia effect on the viability of human normal breast (MCF-10A) ...
Background: Radiotherapy is an integral part of breast cancer treatment. Immune activating propertie...
Background Radiotherapy is an integral part of breast cancer treatment. Immune activating propert...
Background: Radiotherapy, administered in fractionated as well as ablative settings, is an essential...
The treatment of breast cancer by radiotherapy can be complemented by hyperthermia. Little is known ...
The major goal of radiotherapy is the induction of tumor cell death. Additionally, radiotherapy can ...
Multimodal tumor treatment settings consisting of radiotherapy and immunomodulating agents such as i...
It is generally accepted that radiotherapy must target clonogenic cells, i.e., those cells in a tumo...
A systemic immune related response (SIME) of radiotherapy has been occasionally observed on metastat...
Objective The goal of this study is to better understand the immunogenetic expression and related cy...
PURPOSE: Hyperthermia (HT) treatment of cancer patients was revived over the last years and has been...
Radiotherapy is an important therapeutic option for the treatment of cancer. Growing evidence indica...
The major goal of radiotherapy is the induction of tumor cell death. Additionally, radiotherapy can ...
It is becoming increasingly evident that radiotherapy may benefit from coincident or subsequent immu...
Recent advancement in the radiotherapy technology has allowed conformal delivery of high doses of io...
Objective: In this study, the hyperthermia effect on the viability of human normal breast (MCF-10A) ...