Background: Pathogenic yersiniae (Y. pestis, Y. pseudotuberculosis, Y. enterocolitica) share a virulence plasmid encoding a type three secretion system (T3SS). This T3SS comprises more than 40 constituents. Among these are the transport substrates called Yops (Yersinia outer proteins), the specific Yop chaperones (Sycs), and the Ysc (Yop secretion) proteins which form the transport machinery. The effectors YopO and YopP are encoded on an operon together with SycO, the chaperone of YopO. The characterization of SycO is the focus of this study. Results: We have established the large- scale production of recombinant SycO in its outright form. We confirm that Y. enterocolitica SycO forms homodimers which is typical for Syc chaperones. SycO over...
The type III secretion system (T3SS) is a highly conserved secretion system among Gram negative bact...
Yersinia enterocolitica O:8 has two contact-dependent type III secretion systems (TTSSs). The Ysa TT...
Several pathogenic Gram-negative bacteria invest in sophisticated type III secretion systems (T3SS) ...
Background: Pathogenic yersiniae (Y. pestis, Y. pseudotuberculosis, Y. enterocolitica) share a virul...
Background: Pathogenic yersiniae (Y. pestis, Y. pseudotuberculosis, Y. enterocolitica) share a virul...
An ever increasing number of Gram-negative bacteria is known to utilise one or several type three se...
Yersinia bacteria target Yop effector toxins to the interior of host immune cells by the Ysc-Yop typ...
Type III secretion systems harbored by several Gram-negative bacteria are often used to deliver host...
The type III secretion (T3S) system is essential to the virulence of a large number of Gram-negative...
Pathogenic yersiniae utilize a type three secretion system (T3SS) to inject Yop proteins into host c...
Type III secretion is a tightly controlled virulence mechanism utilized by many gram negative bacter...
Various Gram-negative bacteria utilize type III secretion system (T3SS) to deliver effectors into eu...
Successful establishment of Yersinia infections requires the type III machinery, a protein transport...
A plasmid-encoded Type III Secretion System (T3SS) is employed by human pathogenic yersiniae to inje...
Introduction:Yersinia enterocolitica is an opportunistic pathogen which causes enteric diseases like...
The type III secretion system (T3SS) is a highly conserved secretion system among Gram negative bact...
Yersinia enterocolitica O:8 has two contact-dependent type III secretion systems (TTSSs). The Ysa TT...
Several pathogenic Gram-negative bacteria invest in sophisticated type III secretion systems (T3SS) ...
Background: Pathogenic yersiniae (Y. pestis, Y. pseudotuberculosis, Y. enterocolitica) share a virul...
Background: Pathogenic yersiniae (Y. pestis, Y. pseudotuberculosis, Y. enterocolitica) share a virul...
An ever increasing number of Gram-negative bacteria is known to utilise one or several type three se...
Yersinia bacteria target Yop effector toxins to the interior of host immune cells by the Ysc-Yop typ...
Type III secretion systems harbored by several Gram-negative bacteria are often used to deliver host...
The type III secretion (T3S) system is essential to the virulence of a large number of Gram-negative...
Pathogenic yersiniae utilize a type three secretion system (T3SS) to inject Yop proteins into host c...
Type III secretion is a tightly controlled virulence mechanism utilized by many gram negative bacter...
Various Gram-negative bacteria utilize type III secretion system (T3SS) to deliver effectors into eu...
Successful establishment of Yersinia infections requires the type III machinery, a protein transport...
A plasmid-encoded Type III Secretion System (T3SS) is employed by human pathogenic yersiniae to inje...
Introduction:Yersinia enterocolitica is an opportunistic pathogen which causes enteric diseases like...
The type III secretion system (T3SS) is a highly conserved secretion system among Gram negative bact...
Yersinia enterocolitica O:8 has two contact-dependent type III secretion systems (TTSSs). The Ysa TT...
Several pathogenic Gram-negative bacteria invest in sophisticated type III secretion systems (T3SS) ...