Comparison of normal and dusty day impacts on fractional exhaled nitric oxide and lung function in healthy children in Ahvaz, Iran

Abstract Children are the vulnerable group at risk of adverse health effects related to air pollution due to dust storm in Ahvaz. The purpose of this study was to compare the values of fractional exhaled nitric oxide (FENO) and lung functionsas parameters of adverse health effects of particulate matter(PM) in dusty and normal (non-dusty) days in elementaryschoolchildren. The study was conducted among elementaryschool students in Ahvaz. The healthy elementary schoolchildren (N = 105) were selected from different districtsfor FENO and lung function sampling during the dusty andnormal days. The values of PM10 and PM2.5 during dusty dayswere higher than during normal days. Mean values of FENOduring the normal and dusty days were 14.23 and 20.3 ppb,respectively, and the difference between these values was statisticallysignificant (p < 0.05). Lung function results showeda statistically significant difference between the mean valuesof forced vital capacity during the dusty and normal days(p < 0.05). The results revealed a significant difference bothin the values of inflammatory biomarker and in the lung function tests in dusty and normal days. Based on our results,fractional exhaled nitric oxide could be a useful short-term biomarker of particulate pollution effect coupled with spirometry