Allogeneic hematopoietic stem cell transplantation (allo-HSCT) may be curative, but is associated with significant morbidity and mortality. Chronic graft-versus-host disease (cGvHD), characterized by inflammation and fibrosis of multiple target organs, considerably contributes to the morbidity and mortality even years after allo-HSCT. Diagnosis of cGvHD is based on clinical features and histology of biopsies. Here, we report the generation of a urinary cGvHD-specific proteome-pattern (cGvHD_MS14) established by capillary electrophoresis-mass spectrometry to predict onset and severity of cGvHD as an unbiased laboratory test. cGvHD_MS14 was evaluated on samples from 412 patients collected prospectively in four transplant centers. Sensitivity ...
Despite recent advancements in human immune-genetics, graft-versus-host disease (GvHD) continues to ...
Abstract We studied serum proteomic profiling in patients with graft versus...
Biomarkers are increasingly used for diagnosis and treatment of transplant-related complications inc...
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) may be curative, but is associated wi...
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is one curative treatment for hematol...
Improved diagnostic and treatment methods are needed for chronic graft-versus-host disease (cGVHD), ...
Allogeneic hematopoietic stem cell transplantation (HSCT) is the most effective form of tumor immuno...
Acute graft versus host disease (GVHD) remains a major complication of allogeneic hematopoietic cell...
Graft-versus-host disease (GVHD) is the major life-threatening complication after allogeneic hematop...
Graft-versus-host disease (GVHD) is the major life-threatening complication after allogeneic hematop...
Graft-versus-host disease (GVHD) is the major life-threatening complication after allogeneic hematop...
Acute and chronic graft versus host disease (GVHD) are serious complications of allogeneic hematopoi...
AbstractGraft-versus-host disease (GVHD) is the major life-threatening complication after allogeneic...
Prognostic, diagnostic or predictive biomarkers are urgently needed for assessment of chronic graft-...
Graft versus Host Disease (GvHD) is the major life threatening complication after allogeneic stem ce...
Despite recent advancements in human immune-genetics, graft-versus-host disease (GvHD) continues to ...
Abstract We studied serum proteomic profiling in patients with graft versus...
Biomarkers are increasingly used for diagnosis and treatment of transplant-related complications inc...
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) may be curative, but is associated wi...
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is one curative treatment for hematol...
Improved diagnostic and treatment methods are needed for chronic graft-versus-host disease (cGVHD), ...
Allogeneic hematopoietic stem cell transplantation (HSCT) is the most effective form of tumor immuno...
Acute graft versus host disease (GVHD) remains a major complication of allogeneic hematopoietic cell...
Graft-versus-host disease (GVHD) is the major life-threatening complication after allogeneic hematop...
Graft-versus-host disease (GVHD) is the major life-threatening complication after allogeneic hematop...
Graft-versus-host disease (GVHD) is the major life-threatening complication after allogeneic hematop...
Acute and chronic graft versus host disease (GVHD) are serious complications of allogeneic hematopoi...
AbstractGraft-versus-host disease (GVHD) is the major life-threatening complication after allogeneic...
Prognostic, diagnostic or predictive biomarkers are urgently needed for assessment of chronic graft-...
Graft versus Host Disease (GvHD) is the major life threatening complication after allogeneic stem ce...
Despite recent advancements in human immune-genetics, graft-versus-host disease (GvHD) continues to ...
Abstract We studied serum proteomic profiling in patients with graft versus...
Biomarkers are increasingly used for diagnosis and treatment of transplant-related complications inc...