Peroxisomes are organelles best known for their essential roles in lipid metabolism and hydrogen peroxide detoxification. Peroxisomal biogenesis in the yeast Yarrowia lipolytica is a multi-step process of temporally ordered sequential conversion of five distinct peroxisomal subforms, termed P1 to P5, into a mature peroxisomal subform P6 carrying the complete set of matrix and membrane proteins. In the first part of my thesis, I investigate the effect of lateral heterogeneity of the peroxisomal membrane bilayer on the efficiency of the fusion between P1 and P2 in the yeast Y. lipolytica. My findings provide a unique view of the multistep remodeling of the protein repertoire of ergosterol- and ceramide-rich (ECR) domains found in the peroxis...
The application of yeast as a model organism for studying eukaryotic pathways, notably mechanisms an...
Peroxisomes are cell organelles that are present in almost all eukaryotic cells and involved in a la...
This thesis describes studies in which the budding yeast Saccharomyces cerevisiae was used as a mode...
Proper control of lipid metabolism in the endoplasmic reticulum, lipid bodies, peroxisomes and mitoc...
Acyl-CoA oxidase (Aox) is an enzyme that carries out the first step of Ý-oxidation of free fatty aci...
Ageing is characterized by the progressive decline in cellular functions that eventually leads to de...
SummaryWe studied the chronological lifespan of glucose-grown Saccharomyces cerevisiae in relation t...
In studies presented in this Thesis, I developed novel methods of liquid chromatography coupled with...
This thesis describes studies that have resulted in uncovering molecular and cellular mechanisms und...
Recent studies have revealed that different classes of lipids play essential roles in the intrinsica...
Antioxidant enzymes play a critical role in stress response and cell viability by controlling intrac...
Peroxisomes are ubiquitous cell organelles that play a central role in cellular lipid and hydrogen p...
This thesis describes studies in which the yeast Saccharomyces cerevisiae was used as a model organi...
Peroxisomes are compartments in cells called organelles that perform many different functions. In hu...
Peroxisomes are ubiquitous eukaryotic organelles, which perform a plethora of functions including hy...
The application of yeast as a model organism for studying eukaryotic pathways, notably mechanisms an...
Peroxisomes are cell organelles that are present in almost all eukaryotic cells and involved in a la...
This thesis describes studies in which the budding yeast Saccharomyces cerevisiae was used as a mode...
Proper control of lipid metabolism in the endoplasmic reticulum, lipid bodies, peroxisomes and mitoc...
Acyl-CoA oxidase (Aox) is an enzyme that carries out the first step of Ý-oxidation of free fatty aci...
Ageing is characterized by the progressive decline in cellular functions that eventually leads to de...
SummaryWe studied the chronological lifespan of glucose-grown Saccharomyces cerevisiae in relation t...
In studies presented in this Thesis, I developed novel methods of liquid chromatography coupled with...
This thesis describes studies that have resulted in uncovering molecular and cellular mechanisms und...
Recent studies have revealed that different classes of lipids play essential roles in the intrinsica...
Antioxidant enzymes play a critical role in stress response and cell viability by controlling intrac...
Peroxisomes are ubiquitous cell organelles that play a central role in cellular lipid and hydrogen p...
This thesis describes studies in which the yeast Saccharomyces cerevisiae was used as a model organi...
Peroxisomes are compartments in cells called organelles that perform many different functions. In hu...
Peroxisomes are ubiquitous eukaryotic organelles, which perform a plethora of functions including hy...
The application of yeast as a model organism for studying eukaryotic pathways, notably mechanisms an...
Peroxisomes are cell organelles that are present in almost all eukaryotic cells and involved in a la...
This thesis describes studies in which the budding yeast Saccharomyces cerevisiae was used as a mode...