The current paper details a succinct characterisation of an in-house designed microfluidic culture device. The maintenance of tissue viability was determined by studying single cells, following dissociation, of head and neck tumour pre and post culture. In addition, irradiation schedules have been elucidated using cell lines for transfer to the on-chip model. This provides a platform for a move towards personalised medicine in which the interrogation of biopsies on-chip will provide an evidence-base for treatment. (Fig 1.)
Aim: Head and neck squamous cell carcinomas (HNSCC) are solid tumors with low overall survival (40–6...
Lab-on-chip systems are microfluidic devices that can be used as powerful tools for research in fiel...
Tailoring patient‐specific treatments for cancer is necessary in order to achieve optimal results bu...
The current paper details a succinct characterisation of an in-house designed microfluidic culture d...
We report the novel use of a custom-made microfluidic based device to maintain biopsies of head and ...
Tumors are heterogeneous masses of cells characterized pathologically by their size and spread. Thei...
Whilst a multitude of techniques have been employed to study the biology of tumour tissue and its re...
This paper presents the development of a microfluidic device capable of maintaining long-term cultur...
Development of personalised cancer models to predict response to radiation would benefit patient car...
Microfluidic devices, such as lab-on-a-chip systems, are highly advantageous for cell engineering an...
The objective of this project is to design and fabricate lab-on-a-chip devices for culturing cancer ...
In this project, the microfludic cell culture chip and array has been designed and fabricated by co...
Optimal treatment of cancer requires diagnostic methods to facilitate therapy choice and prevent ine...
Currently most cell-based methodologies in microfluidic systems utilize homogeneous or heterogeneous...
Organ-on-chip systems are capable of replicating complex tissue structures and physiological phenome...
Aim: Head and neck squamous cell carcinomas (HNSCC) are solid tumors with low overall survival (40–6...
Lab-on-chip systems are microfluidic devices that can be used as powerful tools for research in fiel...
Tailoring patient‐specific treatments for cancer is necessary in order to achieve optimal results bu...
The current paper details a succinct characterisation of an in-house designed microfluidic culture d...
We report the novel use of a custom-made microfluidic based device to maintain biopsies of head and ...
Tumors are heterogeneous masses of cells characterized pathologically by their size and spread. Thei...
Whilst a multitude of techniques have been employed to study the biology of tumour tissue and its re...
This paper presents the development of a microfluidic device capable of maintaining long-term cultur...
Development of personalised cancer models to predict response to radiation would benefit patient car...
Microfluidic devices, such as lab-on-a-chip systems, are highly advantageous for cell engineering an...
The objective of this project is to design and fabricate lab-on-a-chip devices for culturing cancer ...
In this project, the microfludic cell culture chip and array has been designed and fabricated by co...
Optimal treatment of cancer requires diagnostic methods to facilitate therapy choice and prevent ine...
Currently most cell-based methodologies in microfluidic systems utilize homogeneous or heterogeneous...
Organ-on-chip systems are capable of replicating complex tissue structures and physiological phenome...
Aim: Head and neck squamous cell carcinomas (HNSCC) are solid tumors with low overall survival (40–6...
Lab-on-chip systems are microfluidic devices that can be used as powerful tools for research in fiel...
Tailoring patient‐specific treatments for cancer is necessary in order to achieve optimal results bu...