Feasibility and acceptability of a beverage intervention for Hispanic adults: results from a pilot randomized controlled trial

Objective To assess the feasibility and acceptability of a beverage intervention in Hispanic adults. Design Eligible individuals identified as Hispanic, were 18-64 years old and had BMI 30.0-50.0 kg/m(2). Participants were randomized 2:2:1 to one of three beverages: Mediterranean lemonade (ML), green tea (GT) or flavoured water control (FW). After a 2-week washout period, participants were asked to consume 32 oz (946 ml) of study beverage daily for 6 weeks and avoid other sources of tea, citrus, juice and sweetened beverages; water was permissible. Fasting blood samples were collected at baseline and 8 weeks to assess primary and secondary efficacy outcomes. Setting Tucson, AZ, USA. Participants Fifty-two participants were recruited over 6 months; fifty were randomized (twenty-one ML, nineteen GT, ten FW). Study population mean (sd) age 44.6 (sd 10.2) years, BMI 35.9 (4.6) kg/m(2); 78 % female. Results Forty-four (88 %) completed the 8-week assessment. Self-reported adherence was high. No significant change (95 % CI) in total cholesterol (mg/dl) from baseline was shown -1.7 (-14.2, 10.9), -3.9 (-17.2, 9.4) and -13.2 (-30.2, 3.8) for ML, GT and FW, respectively. Mean change in HDL-cholesterol (mg/dl) -2.3 (-5.3, 0.7; ML), -1.0 (-4.2, 2.2; GT), -3.9 (-8.0, 0.2; FW) and LDL-cholesterol (mg/dl) 0.2 (-11.3, 11.8; ML), 0.5 (-11.4, 12.4; GT), -9.8 (-25.0, 5.4; FW) were also non-significant. Fasting glucose (mg/dl) increased significantly by 5.2 (2.6, 7.9; ML) and 3.3 (0.58, 6.4; GT). No significant change in HbA1c was demonstrated. Due to the small sample size, potential confounders and effect modifiers were not investigated. Conclusions Recruitment and retention figures indicate that a larger-scale trial is feasible; however, favourable changes in cardiometabolic biomarkers were not demonstrated.University of Arizona Mel and Enid Zuckerman College of Public Health through the Diabetes Development Fund12 month embargo; published online: 19 November 2018This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu