Regio- and Enantioselective Formal Hydroamination of Enamines for the Synthesis of 1,2-Diamines

  • Yu, Lu
  • Somfai, Peter
Publication date
January 2019
Publisher
John Wiley & Sons Inc.

Abstract

The asymmetric formal hydroamination of enamines using a CuH catalyst is reported. The method provides a straightforward and efficient approach to the synthesis of chiral 1,2-dialkyl amines in good yields with high levels of enantioselectivities for a broad range of substrates, and should have significant value for the preparation of molecules bearing a 1,2-diamine motif

Extracted data

We use cookies to provide a better user experience.