Impact on life expectancy of HIV-1 positive individuals of CD4R cell count and viral load response to antiretroviral therapy
- May, Margaret T.
- Gompels, Mark
- Delpech, Valerie
- Porter, Kholoud
- Orkin, Chloe
- Kegg, Stephen
- Hay, Phillip
- Johnson, Margaret
- Palfreeman, Adrian
- Gilson, Richard
- Chadwick, David
- Martin, Fabiola
- Hill, Teresa
- Walsh, John
- Post, Frank
- Fisher, Martin
- Ainsworth, Jonathan
- Jose, Sophie
- Leen, Clifford
- Nelson, Mark
- Anderson, Jane
- Sabin, Caroline
- Babiker, Abdel
- Dunn, Daviad
- Gazzard, Brian
- Phillips, Andrew
- Pillay, Deenan
- Sachikonye, Memory
- Schwenk, Achim
- Winston, Alan
- Mackie, Nicky
Publication date
May 2014
DOI Publisher
Ovid Technologies (Wolters Kluwer Health)Abstract
Objective: The objective of this study is to estimate life expectancies of HIV-positive patients conditional on response to antiretroviral therapy (ART). Methods: Patients aged more than 20 years who started ART during 2000-2010 (excluding IDU) in HIV clinics contributing to the UK CHIC Study were followed for mortality until 2012.Wedetermined the latestCD4+ cell count and viral load before ART and in each of years 1-5 of ART. For each duration of ART, life tables based on estimated mortality rates by sex, age, latest CD4+ cell count and viral suppression (HIV-1 RN
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