Graphene is a 2D material possessing extraordinary electrical, mechanical and optical properties which paves way for biomedical applications. A well-known method to fabricate graphene-based devices is depositing graphene using chemical vapor deposition and transferring it to any substrate using polymer support like PMMA (Polymethyl methacrylate) or PDMS (Polydimethylsiloxane). In this process multiple wetting and drying steps are required which compromises the quality of graphene. Also, PMMA leaves residues that are difficult to remove. Here, we report a novel method to fabricate graphene sensors inside PDMS channels. In this method graphene/copper stack is bonded on a PDMS surface using mechanical pressure and temperature. This PDMS layer ...