Lipids in extracellular matrices (ECM) contribute to barrier function and stability of epithelial tissues such as the pulmonary alveoli and the skin. In insects, skin waterproofness depends on the outermost layer of the extracellular cuticle termed envelope that contains cuticulin, an unidentified water-repellent complex molecule composed of proteins, lipids and catecholamines. Based on live-imaging analyses of fruit fly larvae, we find that initially envelope units are assembled within putative vesicles harbouring the ABC transporter Snu and the extracellular protein Snsl. In a second step, the content of these vesicles is distributed to cuticular lipid-transporting nanotubes named pore canals and to the cuticle surface in dependence of Sn...
The apical plasma membrane of epithelial cells plays a central role in producing and shaping the api...
Under conditions of stress, many animals suffer from epithelial barrier disruption that can cause mo...
The cuticle forms an apical extracellular-matrix (ECM) that covers exposed organs, such as epidermis...
Lipids in extracellular matrices (ECM) contribute to barrier function and stability of epithelial ti...
Prevention of desiccation is a constant challenge for terrestrial organisms. Land insects have an ex...
Prevention of desiccation is a constant challenge for terrestrial organisms. Land insects have an ex...
Prevention of desiccation is a constant challenge for terrestrial organisms. Land insects have an ex...
WOS:000514903300012.International audiencePrevention of desiccation is a constant challenge for terr...
This article is part of the Research Topic "Genetic and Epigenetic Regulation of Insect Development,...
Cuticular hydrocarbons (CHCs) play a critical role in the establishment of the waterproof barrier th...
The outer surface of insects is covered by the cuticle, which is derived from the apical extracellul...
The outer surface of insects is covered by the cuticle, which is derived from the apical extracellul...
The stability of extracellular matrices is in general ensured by cross-linking of its components. Pr...
The integument protects the organism against penetration of xenobiotics and water that would potenti...
Background: The differentiation of an extracellular matrix (ECM) at the apical side of epithelial ce...
The apical plasma membrane of epithelial cells plays a central role in producing and shaping the api...
Under conditions of stress, many animals suffer from epithelial barrier disruption that can cause mo...
The cuticle forms an apical extracellular-matrix (ECM) that covers exposed organs, such as epidermis...
Lipids in extracellular matrices (ECM) contribute to barrier function and stability of epithelial ti...
Prevention of desiccation is a constant challenge for terrestrial organisms. Land insects have an ex...
Prevention of desiccation is a constant challenge for terrestrial organisms. Land insects have an ex...
Prevention of desiccation is a constant challenge for terrestrial organisms. Land insects have an ex...
WOS:000514903300012.International audiencePrevention of desiccation is a constant challenge for terr...
This article is part of the Research Topic "Genetic and Epigenetic Regulation of Insect Development,...
Cuticular hydrocarbons (CHCs) play a critical role in the establishment of the waterproof barrier th...
The outer surface of insects is covered by the cuticle, which is derived from the apical extracellul...
The outer surface of insects is covered by the cuticle, which is derived from the apical extracellul...
The stability of extracellular matrices is in general ensured by cross-linking of its components. Pr...
The integument protects the organism against penetration of xenobiotics and water that would potenti...
Background: The differentiation of an extracellular matrix (ECM) at the apical side of epithelial ce...
The apical plasma membrane of epithelial cells plays a central role in producing and shaping the api...
Under conditions of stress, many animals suffer from epithelial barrier disruption that can cause mo...
The cuticle forms an apical extracellular-matrix (ECM) that covers exposed organs, such as epidermis...