The relationship between transmission time and clustering methods in Mycobacterium tuberculosis epidemiology
- Meehan, C.
- Moris, P.
- Kohl, T.
- Pečerska, J.
- Akter, S.
- Merker, M.
- Utpatel, C.
- Beckert, P.
- Gehre, F.
- Lempens, P.
- Stadler, T.
- Kaswa, M.
- Kühnert, D.
- Niemann, S.
- de Jong
- C., B.
DOIAbstract
BackgroundTracking recent transmission is a vital part of controlling widespread pathogens such as Mycobacterium tuberculosis. Multiple methods with specific performance characteristics exist for detecting recent transmission chains, usually by clustering strains based on genotype similarities. With such a large variety of methods available, informed selection of an appropriate approach for determining transmissions within a given setting/time period is difficult
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