The CONNECT project: Combining macro- and micro-structure
- Assaf, Y.
- Alexander, D.
- Jones, D.
- Bizzi, A.
- Behrens, T.
- Clark, C.
- Cohen, Y.
- Dyrby, T.
- Huppi, P.
- Knösche, T.
- LeBihan, D.
- Parker, G.
- Poupon, C.
- Anaby, D.
- Anwander, A.
- Bar, L.
- Barazany, D.
- Blumenfeld-Katzir, T.
- De-Santis, S.
- Duclap, D.
- Figini, M.
- Fischi, E.
- Guevara, P.
- Hubbard, P.
- Hofstetter, S.
- Jbabdi, S.
- Kunz, N.
- Lazeyras, F.
- Lebois, A.
- Liptrot, M.
- Lundell, H.
- Mangin, J.
- Moreno-Dominguez, D.
- Morozov, D.
- Schreiber, J.
- Seunarine, K.
- Nava, S.
- Poupon, C.
- Riffert, T.
- Sasson, E.
- Schmitt, B.
- Shemesh, N.
- Sotiropoulos, S.
- Tavora, I.
- Zhang, H.
- Zhou, F.
DOIAbstract
In recent years, diffusion MRI has become an extremely important tool for studying the morphology of living brain tissue, as it provides unique insights into both its macrostructure and microstructure. Recent applications of diffusion MRI aimed to characterize the structural connectome using tractography to infer connectivity between brain regions. In parallel to the development of tractography, additional diffusion MRI based frameworks (CHARMED, AxCaliber, ActiveAx) were developed enabling the extraction of a multitude of micro-structural parameters (axon diameter distribution, mean axonal diameter and axonal density). This unique insight into both tissue microstructure and connectivity has enormous potential value in understanding the str...
Add to ORKG