Plant viruses are emerging as versatile tools for nanotechnology applications since it is possible to modify their multivalent protein surfaces and thereby introduce and display new functionalities. In this chapter, we describe a tobacco mosaic virus (TMV) variant that exposes two selectively addressable amino acid moieties on each of its 2130 coat protein (CP) subunits. A lysine as well as a cysteine introduced at accessible sites of every CP can be modified with amino- and/or thiol-reactive chemistry such as N-hydroxysuccinimide esters (NHS ester) and maleimide containing reagents alone or simultaneously. This enables the pairwise immobilization of distinct molecules in close vicinity to each other on the TMV surface by simple standard co...
AbstractElectrostatic repulsion between carboxylate groups across subunit interfaces has for many ye...
The tobacco mosaic virus (TMV) is one of the most studied virus. Its properties (simplicity, self as...
The self-assembling protein shells of viruses have provided convenient scaffolds for the constructio...
Tobacco mosaic virus (TMV) is a robust nanotubular nucleoprotein scaffold increasingly employed for ...
The rod-shaped nanoparticles of the widespread plant pathogen tobacco mosaic virus (TMV) have been a...
The spacing of functional nanoscopic elements may play a fundamental role in nanotechnological and b...
AbstractDisplay of peptides or proteins in an ordered, repetitive array, such as on the surface of a...
Abstract Virus-like particles are an emerging class of nano-biotechnology with the Tobacco Mosaic Vi...
Plant virus nanoparticles are promising candidates for the development of novel materials, including...
A method for site-specific and high yield modification of tobacco mosaic virus coat protein (TMVCP) ...
Nanoparticle multifunctionalization has become an important goal in many nanoscience-related areas b...
We have genetically engineered the capsid proteins (CPs) of two RNA-packaging plant viruses, BMV and...
Plant virus nanoparticles (VNPs) have many unique advantages, including their ability to self-assemb...
Jockusch H, Wiegand C. Misfolded plant virus proteins: elicitors and targets of ubiquitylation. FEBS...
Using tobacco mosaic virus coat proteins (TMVcp) from both sources of the plant and bacterial expres...
AbstractElectrostatic repulsion between carboxylate groups across subunit interfaces has for many ye...
The tobacco mosaic virus (TMV) is one of the most studied virus. Its properties (simplicity, self as...
The self-assembling protein shells of viruses have provided convenient scaffolds for the constructio...
Tobacco mosaic virus (TMV) is a robust nanotubular nucleoprotein scaffold increasingly employed for ...
The rod-shaped nanoparticles of the widespread plant pathogen tobacco mosaic virus (TMV) have been a...
The spacing of functional nanoscopic elements may play a fundamental role in nanotechnological and b...
AbstractDisplay of peptides or proteins in an ordered, repetitive array, such as on the surface of a...
Abstract Virus-like particles are an emerging class of nano-biotechnology with the Tobacco Mosaic Vi...
Plant virus nanoparticles are promising candidates for the development of novel materials, including...
A method for site-specific and high yield modification of tobacco mosaic virus coat protein (TMVCP) ...
Nanoparticle multifunctionalization has become an important goal in many nanoscience-related areas b...
We have genetically engineered the capsid proteins (CPs) of two RNA-packaging plant viruses, BMV and...
Plant virus nanoparticles (VNPs) have many unique advantages, including their ability to self-assemb...
Jockusch H, Wiegand C. Misfolded plant virus proteins: elicitors and targets of ubiquitylation. FEBS...
Using tobacco mosaic virus coat proteins (TMVcp) from both sources of the plant and bacterial expres...
AbstractElectrostatic repulsion between carboxylate groups across subunit interfaces has for many ye...
The tobacco mosaic virus (TMV) is one of the most studied virus. Its properties (simplicity, self as...
The self-assembling protein shells of viruses have provided convenient scaffolds for the constructio...