Little is know about the regulation of SUMO E3 ligases and how they are activated upon stress. New findings from the Reverter and Torres-Rosell laboratories in The EMBO Journal demonstrate the vicinity of preferentially ssDNA activates the SUMO E3 ligase Nse2 when in complex with SMC5-6
Protein sumoylation, especially when catalyzed by the Mms21 SUMO E3 ligase, plays a major role in su...
International audienceThe SLX4 Fanconi anemia protein is a tumor suppres- sor that may act as a key ...
Evolutionary pressures have caused eukaryotic cells to develop various response mechanisms to changi...
Little is known about the regulation of SUMO E3 ligases and how they are activated upon stress. New ...
Modification of chromosomal proteins by conjugation to SUMO is a key step to cope with DNA damage an...
SUMO chains act as stress-induced degradation tags or repair factor–recruiting signals at DNA lesion...
Sp3 is a ubiquitous transcription factor closely related to Sp1. Here we show that Sp3 is a target f...
Sp3 is a ubiquitous transcription factor closely related to Sp1. Here we show that Sp3 is a target f...
Abstract Background Conjugation of small ubiquitin-related modifiers (SUMOs) is a frequent post-tran...
The Schizosaccharomyces pombe SMC proteins Rad18 (Smc6) and Spr18 (Smc5) exist in a high-M(r) comple...
Genetic information encoded in chromosomal DNA is challenged by intrinsic and exogenous sources of D...
Small ubiquitin-like modifier (SUMO) conjugation is a reversible post-translational modification pro...
Small ubiquitin-like modifier (SUMO)ylation is a reversible post-translational modification that pla...
SUMO (Small Ubiquitin-like Modifier) is a post-translational modifier, which is conjugated to its ta...
Modification of proteins by SUMO is essential for the maintenance of genome integrity. During DNA re...
Protein sumoylation, especially when catalyzed by the Mms21 SUMO E3 ligase, plays a major role in su...
International audienceThe SLX4 Fanconi anemia protein is a tumor suppres- sor that may act as a key ...
Evolutionary pressures have caused eukaryotic cells to develop various response mechanisms to changi...
Little is known about the regulation of SUMO E3 ligases and how they are activated upon stress. New ...
Modification of chromosomal proteins by conjugation to SUMO is a key step to cope with DNA damage an...
SUMO chains act as stress-induced degradation tags or repair factor–recruiting signals at DNA lesion...
Sp3 is a ubiquitous transcription factor closely related to Sp1. Here we show that Sp3 is a target f...
Sp3 is a ubiquitous transcription factor closely related to Sp1. Here we show that Sp3 is a target f...
Abstract Background Conjugation of small ubiquitin-related modifiers (SUMOs) is a frequent post-tran...
The Schizosaccharomyces pombe SMC proteins Rad18 (Smc6) and Spr18 (Smc5) exist in a high-M(r) comple...
Genetic information encoded in chromosomal DNA is challenged by intrinsic and exogenous sources of D...
Small ubiquitin-like modifier (SUMO) conjugation is a reversible post-translational modification pro...
Small ubiquitin-like modifier (SUMO)ylation is a reversible post-translational modification that pla...
SUMO (Small Ubiquitin-like Modifier) is a post-translational modifier, which is conjugated to its ta...
Modification of proteins by SUMO is essential for the maintenance of genome integrity. During DNA re...
Protein sumoylation, especially when catalyzed by the Mms21 SUMO E3 ligase, plays a major role in su...
International audienceThe SLX4 Fanconi anemia protein is a tumor suppres- sor that may act as a key ...
Evolutionary pressures have caused eukaryotic cells to develop various response mechanisms to changi...