Amyloid-β plaques are classical hallmarks of the post-mortem Alzheimer’s Disease (AD) brain. Ultra-High-Field (UHF) MRI provides a compelling means to investigate pathological processes at an unprecedented level of detail. ß-amyloid plaques can be detected in T2* weighted images at UHF, ex-vivo, due to the local iron content and to the plaque geometry per sè. With this study we aim to explore the source of the observed MR signal changes in AD at UHF using quantitative MRI methods in-vivo and ex-vivo
Alzheimer's disease (AD) affects several important molecules in brain metabolism. The resulting neur...
Abstract Ultra-high-field (UHF) magnetic resonance (MR) scanners, that is, equipment operating at st...
Background: This study explores the magnetostatic properties of the Alzheimer’s disease brain using ...
Alzheimer’s disease (AD) is the most common cause of dementia worldwide. So far, diagnosis of AD is ...
Purpose/Introduction: Conspicuous advances in MRI imaging in the last decade catalyzed the quest for...
Aims and objectives: Alzheimer’s Disease (AD) is the most common cause of dementia worldwide. So far...
We report R2 and R2* in human hippocampus from five unfixed post-mortem Alzheimer's disease (AD) and...
Early detection of β-Amyloid (Aβ) deposits in Alzheimer’s disease (AD) patients may enable treatment...
Beta-amyloid (Aβ) plaques are characteristic of Alzheimer’s Disease (AD) brain and cause effects whi...
PET imaging is an established technique to detect cerebral amyloid-β (Aβ) plaques in vivo. Some prec...
Ultra-High-Field (UHF) MRI provides a potential non-invasive means to investigate Alzheimer’s Diseas...
Abstract: Alzheimer’s disease (AD) affects several important molecules in brain metabolism. The resu...
PET imaging is an established technique to detect cerebral amyloid-β (Aβ) plaques in vivo. Some prec...
Background: Chemical imaging of the human brain has great potential for diagnostic and monitoring pu...
Alterations in regional brain iron are a feature of many neurodegenerative disorders, and provide a...
Alzheimer's disease (AD) affects several important molecules in brain metabolism. The resulting neur...
Abstract Ultra-high-field (UHF) magnetic resonance (MR) scanners, that is, equipment operating at st...
Background: This study explores the magnetostatic properties of the Alzheimer’s disease brain using ...
Alzheimer’s disease (AD) is the most common cause of dementia worldwide. So far, diagnosis of AD is ...
Purpose/Introduction: Conspicuous advances in MRI imaging in the last decade catalyzed the quest for...
Aims and objectives: Alzheimer’s Disease (AD) is the most common cause of dementia worldwide. So far...
We report R2 and R2* in human hippocampus from five unfixed post-mortem Alzheimer's disease (AD) and...
Early detection of β-Amyloid (Aβ) deposits in Alzheimer’s disease (AD) patients may enable treatment...
Beta-amyloid (Aβ) plaques are characteristic of Alzheimer’s Disease (AD) brain and cause effects whi...
PET imaging is an established technique to detect cerebral amyloid-β (Aβ) plaques in vivo. Some prec...
Ultra-High-Field (UHF) MRI provides a potential non-invasive means to investigate Alzheimer’s Diseas...
Abstract: Alzheimer’s disease (AD) affects several important molecules in brain metabolism. The resu...
PET imaging is an established technique to detect cerebral amyloid-β (Aβ) plaques in vivo. Some prec...
Background: Chemical imaging of the human brain has great potential for diagnostic and monitoring pu...
Alterations in regional brain iron are a feature of many neurodegenerative disorders, and provide a...
Alzheimer's disease (AD) affects several important molecules in brain metabolism. The resulting neur...
Abstract Ultra-high-field (UHF) magnetic resonance (MR) scanners, that is, equipment operating at st...
Background: This study explores the magnetostatic properties of the Alzheimer’s disease brain using ...