The midbrain-hindbrain organizer (MHO) is a signalling centre that orchestrates development of the mesencephalic and anterior metencephalic primordia. In recent years, details have been revealed about the molecular nature of these signals, their transmission and reception, and the regulatory processes associated with MHO function. This article reviews recent progress in understanding the genetic and molecular components of the MHO, and how they synergize to control brain development
During embryonic development, organiser centres form at compartment boundaries and provide a source ...
textWe have previously shown that the arcuate organization of cell fates within the ventral midbrai...
The Spemann organizer in amphibians gives rise to the anterior mesendoderm (AME) and is capable of i...
The midbrain-hindbrain organizer (MHO) is a signalling centre that orchestrates development of the m...
A crucial event during the development of the central nervous system (CNS) is the early subdivision ...
Specification of the forebrain, midbrain and hindbrain primordia occurs during gastrulation in respo...
The neuromeric concept of brain formation has become a well-established model to explain how order i...
Distinct neural identities are acquired through progressive restriction of developmental potential u...
To understand the formation of the midbrain-hindbrain boundary (MHB) in the neural plate, which func...
The prospective midbrain-hindbrain border (MHB) in the developing vertebrate brain is demarcated at ...
In vertebrates, the embryonic hindbrain is transiently subdivided along its anterior-posterior (A-P)...
The midbrain is a complex structure where different functions are located. This formation is mainly ...
Corresponding attributes of neural development and function suggest arthropod and vertebrate brains ...
Recent studies have shown that the formation of boundaries between the segments - rhombomeres of the...
The Midbrain Hindbrain Domain (MHD) is a region of the central nervous system consisting of the midb...
During embryonic development, organiser centres form at compartment boundaries and provide a source ...
textWe have previously shown that the arcuate organization of cell fates within the ventral midbrai...
The Spemann organizer in amphibians gives rise to the anterior mesendoderm (AME) and is capable of i...
The midbrain-hindbrain organizer (MHO) is a signalling centre that orchestrates development of the m...
A crucial event during the development of the central nervous system (CNS) is the early subdivision ...
Specification of the forebrain, midbrain and hindbrain primordia occurs during gastrulation in respo...
The neuromeric concept of brain formation has become a well-established model to explain how order i...
Distinct neural identities are acquired through progressive restriction of developmental potential u...
To understand the formation of the midbrain-hindbrain boundary (MHB) in the neural plate, which func...
The prospective midbrain-hindbrain border (MHB) in the developing vertebrate brain is demarcated at ...
In vertebrates, the embryonic hindbrain is transiently subdivided along its anterior-posterior (A-P)...
The midbrain is a complex structure where different functions are located. This formation is mainly ...
Corresponding attributes of neural development and function suggest arthropod and vertebrate brains ...
Recent studies have shown that the formation of boundaries between the segments - rhombomeres of the...
The Midbrain Hindbrain Domain (MHD) is a region of the central nervous system consisting of the midb...
During embryonic development, organiser centres form at compartment boundaries and provide a source ...
textWe have previously shown that the arcuate organization of cell fates within the ventral midbrai...
The Spemann organizer in amphibians gives rise to the anterior mesendoderm (AME) and is capable of i...