Add to ORKGThe localization of a protein is intrinsically linked to its role in the structural and functional organization of the cell. Advances in transgenic technology have streamlined the use of protein localization as a function discovery tool. Here we review the use of large genomic DNA constructs such as bacterial artificial chromosomes as a transgenic platform for systematic tag-based protein function exploration
SummaryUsing an orthogonal tRNA-synthetase pair, unnatural amino acids can be genetically encoded wi...
A large proportion of the genome of most eukaryotic organisms consists of highly repetitive mobile g...
Genome sequencing opened the access to the information contained inside cells. Protein science will ...
The interpretation of genome sequences requires reliable and standardized methods to assess protein ...
SummaryUnderstanding the in vivo dynamics of protein localization and their physical interactions is...
Understanding the in vivo dynamics of protein localization and their physical interactions is import...
en iathe instructions encoded in the genome are read into the extraor-dinary variety of molecular st...
Mapping of the human genome has the potential to transform the traditional methods of genetic epidem...
Genenetic engineering is one of the leading technologies in biological research. Transgenesis, one o...
Accomplishment of the human and mouse genome projects resulted in accumulation of extensive gene seq...
ObjectiveOver the past decade, the development of high-throughput technologies for DNA and protein a...
In biology, localisation is function. Cells display a complex sub-cellular structure with numerous d...
Proteins are the workhorses of the cell, playing crucial roles in virtually every biological process...
Sequence–function relationship in a protein is commonly determined by the three-dimensional protein...
Over the past decade, a battery of powerful tools that encompass forward and reverse genetic approac...
SummaryUsing an orthogonal tRNA-synthetase pair, unnatural amino acids can be genetically encoded wi...
A large proportion of the genome of most eukaryotic organisms consists of highly repetitive mobile g...
Genome sequencing opened the access to the information contained inside cells. Protein science will ...
The interpretation of genome sequences requires reliable and standardized methods to assess protein ...
SummaryUnderstanding the in vivo dynamics of protein localization and their physical interactions is...
Understanding the in vivo dynamics of protein localization and their physical interactions is import...
en iathe instructions encoded in the genome are read into the extraor-dinary variety of molecular st...
Mapping of the human genome has the potential to transform the traditional methods of genetic epidem...
Genenetic engineering is one of the leading technologies in biological research. Transgenesis, one o...
Accomplishment of the human and mouse genome projects resulted in accumulation of extensive gene seq...
ObjectiveOver the past decade, the development of high-throughput technologies for DNA and protein a...
In biology, localisation is function. Cells display a complex sub-cellular structure with numerous d...
Proteins are the workhorses of the cell, playing crucial roles in virtually every biological process...
Sequence–function relationship in a protein is commonly determined by the three-dimensional protein...
Over the past decade, a battery of powerful tools that encompass forward and reverse genetic approac...
SummaryUsing an orthogonal tRNA-synthetase pair, unnatural amino acids can be genetically encoded wi...
A large proportion of the genome of most eukaryotic organisms consists of highly repetitive mobile g...
Genome sequencing opened the access to the information contained inside cells. Protein science will ...