Excessive intake of high-caloric diets as well as subsequent development of obesity and diabetes mellitus may exert a wide range of unfavorable effects on the central nervous system (CNS). It has been suggested that one mechanism in this context is the promotion of neuroinflammation. The potentially harmful effects of such diets were suggested to be mitigated by physical exercise. Here, we conducted a study investigating the effects of physical exercise in a cafeteria-diet mouse model on CNS metabolites by means of in vivo proton magnetic resonance spectroscopy ((HMRS)-H-1). In addition postmortem histologic and real-time (RT)-PCR analyses for inflammatory markers were performed. Cafeteria diet induced obesity and hyperglycemia, which was o...
Background/Objectives: High-fat diet consumption is known to trigger an inflammatory response in the...
Background: In the pathogenesis of central nervous system disorders (e.g., neurodegenerative), an im...
Multiple sclerosis (MS) is a complex neurodegenerative disease of the central nervous system (CNS) a...
Excessive intake of high-caloric diets as well as subsequent development of obesity and diabetes mel...
Excessive intake of high-caloric diets as well as subsequent development of obesity and diabetes mel...
Diet rich in fat and sugar associated to sedentary habits are the main cause of obesity. Obesity is ...
Hyperpalatable diets (HP) impair brain metabolism, and regular physical exercise has an apparent opp...
Hypothalamic inflammation is a potentially important process in the pathogenesis of high-fat diet-in...
AbstractHypothalamic inflammation is a potentially important process in the pathogenesis of high-fat...
Regular physical activity and healthy dietary patterns are commonly recommended for the prevention a...
International audienceVascular brain lesions, present in advanced atherosclerosis, share pathologica...
High-fat diet consumption is known to trigger an inflammatory response in the hypothalamus, which ha...
Abstract Obesity and insulin resistance are risk factors in the development of neurodegenerative dis...
Obesity increases inflammation, both peripherally and centrally, and exercise can ameliorate some of...
A diet high in total fat (HF) reduces hippocampal levels of brain-derived neurotrophic factor (BDNF)...
Background/Objectives: High-fat diet consumption is known to trigger an inflammatory response in the...
Background: In the pathogenesis of central nervous system disorders (e.g., neurodegenerative), an im...
Multiple sclerosis (MS) is a complex neurodegenerative disease of the central nervous system (CNS) a...
Excessive intake of high-caloric diets as well as subsequent development of obesity and diabetes mel...
Excessive intake of high-caloric diets as well as subsequent development of obesity and diabetes mel...
Diet rich in fat and sugar associated to sedentary habits are the main cause of obesity. Obesity is ...
Hyperpalatable diets (HP) impair brain metabolism, and regular physical exercise has an apparent opp...
Hypothalamic inflammation is a potentially important process in the pathogenesis of high-fat diet-in...
AbstractHypothalamic inflammation is a potentially important process in the pathogenesis of high-fat...
Regular physical activity and healthy dietary patterns are commonly recommended for the prevention a...
International audienceVascular brain lesions, present in advanced atherosclerosis, share pathologica...
High-fat diet consumption is known to trigger an inflammatory response in the hypothalamus, which ha...
Abstract Obesity and insulin resistance are risk factors in the development of neurodegenerative dis...
Obesity increases inflammation, both peripherally and centrally, and exercise can ameliorate some of...
A diet high in total fat (HF) reduces hippocampal levels of brain-derived neurotrophic factor (BDNF)...
Background/Objectives: High-fat diet consumption is known to trigger an inflammatory response in the...
Background: In the pathogenesis of central nervous system disorders (e.g., neurodegenerative), an im...
Multiple sclerosis (MS) is a complex neurodegenerative disease of the central nervous system (CNS) a...