The roX RNAs represent one of the paradigm examples of large non-coding RNAs involved in chromatin regulation. Interestingly, roX genes have a dual life. The RNA product is part of the MSL complex required for dosage compensation of the male X chromosome in Drosophila while the genomic location is used as a binding platform for MSL complex assembly. In this review we discuss both aspects of roX function and propose an integrated model for possible mechanisms how these RNAs might be involved in epigenetic regulation of the male X chromosome
<p>In Drosophila melanogaster, where males are XY and females are XX, dosage compensation is acheive...
Dosage compensation in Drosophila is an epigenetic phenomenon utilizing proteins and long noncoding ...
Dosage compensation in Drosophila is an epigenetic phenomenon utilizing proteins and long noncoding ...
The roX RNAs represent one of the paradigm examples of large non-coding RNAs involved in chromatin r...
AbstractBackground: In the male Drosophila, the X chromosome is transcriptionally upregulated to ach...
Most genes along the male single X chromosome in Drosophila are hypertranscribed about two-fold rela...
<div><p>Long non-coding RNAs contribute to dosage compensation in both mammals and <i>Drosophila</i>...
AbstractBackground: In the male Drosophila, the X chromosome is transcriptionally upregulated to ach...
<div><p>Most genes along the male single X chromosome in <em>Drosophila</em> are hypertranscribed ab...
The X chromosome provides an ideal model system to study the contribution of RNA-protein interaction...
AbstractThe Drosophila roX1 gene is X-linked and produces RNAs that are male-specific, somatic, and ...
The X chromosome provides an ideal model system to study the contribution of RNA-protein interaction...
AbstractThe multisubunit MSL dosage compensation complex binds to hundreds of sites along the Drosop...
In Drosophila, the global increase in transcription from the male X chromosome to compensate for its...
Confinement of the X chromosome to a territory for dosage compensation is a prime example of how sub...
<p>In Drosophila melanogaster, where males are XY and females are XX, dosage compensation is acheive...
Dosage compensation in Drosophila is an epigenetic phenomenon utilizing proteins and long noncoding ...
Dosage compensation in Drosophila is an epigenetic phenomenon utilizing proteins and long noncoding ...
The roX RNAs represent one of the paradigm examples of large non-coding RNAs involved in chromatin r...
AbstractBackground: In the male Drosophila, the X chromosome is transcriptionally upregulated to ach...
Most genes along the male single X chromosome in Drosophila are hypertranscribed about two-fold rela...
<div><p>Long non-coding RNAs contribute to dosage compensation in both mammals and <i>Drosophila</i>...
AbstractBackground: In the male Drosophila, the X chromosome is transcriptionally upregulated to ach...
<div><p>Most genes along the male single X chromosome in <em>Drosophila</em> are hypertranscribed ab...
The X chromosome provides an ideal model system to study the contribution of RNA-protein interaction...
AbstractThe Drosophila roX1 gene is X-linked and produces RNAs that are male-specific, somatic, and ...
The X chromosome provides an ideal model system to study the contribution of RNA-protein interaction...
AbstractThe multisubunit MSL dosage compensation complex binds to hundreds of sites along the Drosop...
In Drosophila, the global increase in transcription from the male X chromosome to compensate for its...
Confinement of the X chromosome to a territory for dosage compensation is a prime example of how sub...
<p>In Drosophila melanogaster, where males are XY and females are XX, dosage compensation is acheive...
Dosage compensation in Drosophila is an epigenetic phenomenon utilizing proteins and long noncoding ...
Dosage compensation in Drosophila is an epigenetic phenomenon utilizing proteins and long noncoding ...