Add to ORKGThere is a relation between stress and alcohol drinking. We show that the corticotropin-releasing hormone (CRH) system that mediates endocrine and behavioral responses to stress plays a role in the control of long-term alcohol drinking. In mice lacking a functional CRH1 receptor, stress leads to enhanced and progressively increasing alcohol intake. The effect of repeated stress on alcohol drinking behavior appeared with a delay and persisted throughout life. It was associated with an up-regulation of the N-methyl-D-aspartate receptor subunit NR2B. Alterations in the CRH1 receptor gene and adaptional changes in NR2B subunits may constitute a genetic risk factor for stress-induced alcohol drinking and alcoholi
Alcoholism is a chronic and progressive disorder characterized by periods of excessive drinking, wit...
Early life stress (ELS) is associated with risk of excessive alcohol drinking. However, the genetic ...
The results of many studies support the influence of the corticotropin-releasing factor (CRF) system...
There is a relation between stress and alcohol drinking. We show that the corticotropin-releasing ho...
There is a relation between stress and alcohol drinking. We show that the corticotropin-releasing ho...
Corticotropin-releasing hormone (CRH) and its receptor, CRH receptor-1 (CRHR1), have a key role in a...
none4It is increasingly recognized that anti-reward systems are progressively recruited during the d...
BACKGROUND: A history of alcohol dependence recruits increased voluntary alcohol intake and sensiti...
Stress exposure has been identified as one risk factor for alcohol abuse that may facilitate the tra...
It is increasingly recognized that anti-reward systems (i.e. negative reinforcement through stress a...
Corticotropin-releasing factor (CRF) signaling modulates neurobiological responses to stress and eth...
Alcoholism is a chronic relapsing disorder with substantial heritability. Uncovering gene–environme...
BackgroundCorticotropin releasing factor (CRF) and urocortin play an important role in many stress r...
Abstract — Aims: Stress neurocircuitry may modulate the relationship between alcohol drinking and ch...
Stress exposure has been identified as one risk factor for alcohol abuse that may facilitate the tra...
Alcoholism is a chronic and progressive disorder characterized by periods of excessive drinking, wit...
Early life stress (ELS) is associated with risk of excessive alcohol drinking. However, the genetic ...
The results of many studies support the influence of the corticotropin-releasing factor (CRF) system...
There is a relation between stress and alcohol drinking. We show that the corticotropin-releasing ho...
There is a relation between stress and alcohol drinking. We show that the corticotropin-releasing ho...
Corticotropin-releasing hormone (CRH) and its receptor, CRH receptor-1 (CRHR1), have a key role in a...
none4It is increasingly recognized that anti-reward systems are progressively recruited during the d...
BACKGROUND: A history of alcohol dependence recruits increased voluntary alcohol intake and sensiti...
Stress exposure has been identified as one risk factor for alcohol abuse that may facilitate the tra...
It is increasingly recognized that anti-reward systems (i.e. negative reinforcement through stress a...
Corticotropin-releasing factor (CRF) signaling modulates neurobiological responses to stress and eth...
Alcoholism is a chronic relapsing disorder with substantial heritability. Uncovering gene–environme...
BackgroundCorticotropin releasing factor (CRF) and urocortin play an important role in many stress r...
Abstract — Aims: Stress neurocircuitry may modulate the relationship between alcohol drinking and ch...
Stress exposure has been identified as one risk factor for alcohol abuse that may facilitate the tra...
Alcoholism is a chronic and progressive disorder characterized by periods of excessive drinking, wit...
Early life stress (ELS) is associated with risk of excessive alcohol drinking. However, the genetic ...
The results of many studies support the influence of the corticotropin-releasing factor (CRF) system...