Add to ORKGWe describe the stereoselective synthesis of 4alpha-bromo-5alpha-cholestan-3beta-ol, 21-nor-5alpha-cholestan-3beta-ol, 27-nor-5alpha-cholestan-3beta-ol and 21,27-bisnor-5alpha-cholestan-3beta-ol. In order to clarify the in vivo metabolism of cholesterol, these compounds have been used for feeding experiments in Caenorhabditis elegans. Our preliminary results provide important insights into the metabolism of cholesterol in worms
Fil: Prez, Gastón. Consejo Nacional de Investigaciones Científicas y Técnicas.Fil: Hernandez Cravero...
We describe the stereoselective transformation of diosgenin () to (25R)-Delta(4)-dafachronic acid ()...
AbstractThe nematode Caenorhabditis elegans (C. elegans) has during the last decade emerged as an in...
Cholesterol is essential for the survival of the nematode Caenorhabditis elegans. Recent studies hav...
<div><p>(A) Nematode-specific biosynthesis of 4-methylated sterols from exogenously added cholestero...
Cholesterol-derived hormones, the dafachronic acids, play a major role in controlling the life cycle...
Using a highly stereoselective Evans aldol reaction for the introduction of the stereogenic center a...
Summary: This protocol describes the culturing of the nematode Caenorhabditis elegans (C. elegans) i...
Lipids play important roles in many different aspects of biology. A major model organism to study li...
We report a stereoselective synthesis of the (25S)-cholestenoic-26-acids which are highly efficient ...
The nematode Caenorhabditis elegans requires exogenous cholesterol to survive and its depletion lead...
Mammalian bile acids (BAs) are oxidized metabolites of cholesterol whose amphiphilic properties serv...
LET-767 from Caenorhabditis elegans belongs to a family of short chain dehydrogenases/reductases and...
Statins are compounds prescribed to lower blood cholesterol in millions of patients worldwide. They ...
A mixture of 7a-3H- and 4-'4C-labeled cholesterol was admin-istered intravenously to rats. Chol...
Fil: Prez, Gastón. Consejo Nacional de Investigaciones Científicas y Técnicas.Fil: Hernandez Cravero...
We describe the stereoselective transformation of diosgenin () to (25R)-Delta(4)-dafachronic acid ()...
AbstractThe nematode Caenorhabditis elegans (C. elegans) has during the last decade emerged as an in...
Cholesterol is essential for the survival of the nematode Caenorhabditis elegans. Recent studies hav...
<div><p>(A) Nematode-specific biosynthesis of 4-methylated sterols from exogenously added cholestero...
Cholesterol-derived hormones, the dafachronic acids, play a major role in controlling the life cycle...
Using a highly stereoselective Evans aldol reaction for the introduction of the stereogenic center a...
Summary: This protocol describes the culturing of the nematode Caenorhabditis elegans (C. elegans) i...
Lipids play important roles in many different aspects of biology. A major model organism to study li...
We report a stereoselective synthesis of the (25S)-cholestenoic-26-acids which are highly efficient ...
The nematode Caenorhabditis elegans requires exogenous cholesterol to survive and its depletion lead...
Mammalian bile acids (BAs) are oxidized metabolites of cholesterol whose amphiphilic properties serv...
LET-767 from Caenorhabditis elegans belongs to a family of short chain dehydrogenases/reductases and...
Statins are compounds prescribed to lower blood cholesterol in millions of patients worldwide. They ...
A mixture of 7a-3H- and 4-'4C-labeled cholesterol was admin-istered intravenously to rats. Chol...
Fil: Prez, Gastón. Consejo Nacional de Investigaciones Científicas y Técnicas.Fil: Hernandez Cravero...
We describe the stereoselective transformation of diosgenin () to (25R)-Delta(4)-dafachronic acid ()...
AbstractThe nematode Caenorhabditis elegans (C. elegans) has during the last decade emerged as an in...