Add to ORKGThe proteasome is a macromolecular assembly that is designed to confine proteolytic activity to an inner cavity. Access to the central proteolytic nanocompartment is restricted to unfolded proteins, which necessitates a functional coupling of the 20S proteasome to a substrate-recognition and unfolding machinery. Significant progress has been made during the past two years in elucidating the structural principles and the enzymatic mechanism of the 20S proteasome. [References: 52
In eukaryotes protein degradation is performed by the ubiquitin-proteasome system. The 26S proteasom...
AbstractThe final destination of the majority of proteins that have to be selectively degraded in eu...
The 26S proteasome is a molecular machine of approximately 2.5 MDa, which degrades ubiquitylated pro...
The proteasome is a macromolecular assembly that is designed to confine proteolytic activity to an i...
Significant progress has been made over the past few years in elucidating the structural principles ...
Significant progress has been made over the past few years in elucidating the structural principles ...
Significant progress has been made over the past few years in elucidating the structural principles ...
In eukaryotic cells, the vast majority of proteins in the cytosol and nucleus are degraded via the p...
AbstractThe proteasome is a cellular protease responsible for the selective degradation of the major...
Intracellular proteolysis is an essential process. In eukaryotes, most proteins in the cytosol and n...
Intracellular proteolysis is an essential process. In eukaryotes, most proteins in the cytosol and n...
Intracellular proteolysis is an essential process. In eukaryotes, most proteins in the cytosol and n...
In eukaryotic cells, most proteins in the cytosol and nucleus are degraded via the ubiquitin-proteas...
The ubiquitin-proteasome system is responsible for the targeted degradation of proteins within the c...
The ubiquitin-proteasome system is responsible for the targeted degradation of proteins within the c...
In eukaryotes protein degradation is performed by the ubiquitin-proteasome system. The 26S proteasom...
AbstractThe final destination of the majority of proteins that have to be selectively degraded in eu...
The 26S proteasome is a molecular machine of approximately 2.5 MDa, which degrades ubiquitylated pro...
The proteasome is a macromolecular assembly that is designed to confine proteolytic activity to an i...
Significant progress has been made over the past few years in elucidating the structural principles ...
Significant progress has been made over the past few years in elucidating the structural principles ...
Significant progress has been made over the past few years in elucidating the structural principles ...
In eukaryotic cells, the vast majority of proteins in the cytosol and nucleus are degraded via the p...
AbstractThe proteasome is a cellular protease responsible for the selective degradation of the major...
Intracellular proteolysis is an essential process. In eukaryotes, most proteins in the cytosol and n...
Intracellular proteolysis is an essential process. In eukaryotes, most proteins in the cytosol and n...
Intracellular proteolysis is an essential process. In eukaryotes, most proteins in the cytosol and n...
In eukaryotic cells, most proteins in the cytosol and nucleus are degraded via the ubiquitin-proteas...
The ubiquitin-proteasome system is responsible for the targeted degradation of proteins within the c...
The ubiquitin-proteasome system is responsible for the targeted degradation of proteins within the c...
In eukaryotes protein degradation is performed by the ubiquitin-proteasome system. The 26S proteasom...
AbstractThe final destination of the majority of proteins that have to be selectively degraded in eu...
The 26S proteasome is a molecular machine of approximately 2.5 MDa, which degrades ubiquitylated pro...