Metagenomics enables the study of complex microbial communities from myriad sources, including the remains of oral and gut microbiota preserved in archaeological dental calculus and paleofeces, respectively. While accurate taxonomic assignment is essential to this process, DNA damage, characteristic to ancient samples (e.g. reduction in fragment size), may reduce the accuracy of read taxonomic assignment. Using a set of in silico-generated metagenomic datasets we investigated how the addition of ancient DNA (aDNA) damage patterns influences microbial taxonomic assignment by five widely-used profilers: QIIME/UCLUST, MetaPhlAn2, MIDAS, CLARK-S, and MALT (BLAST-X-mode). In silico-generated datasets were designed to mimic dental plaque, consist...
Studies of human–associated microbial communities are increasingly integrated into biological anthro...
AbstractAssessing the taxonomic composition of metagenomic samples is an important first step in und...
Exploring the genetic diversity of microbes within the environment through metagenomic sequencing fi...
Metagenomics enables the study of complex microbial communities from myriad sources, including the r...
Metagenomics enables the study of complex microbial communities from myriad sources, including the r...
The field of palaeomicrobiology—the study of ancient microorganisms—is rapidly growing due to recent...
To date, characterization of ancient oral (dental calculus) and gut (coprolite) microbiota has been ...
The identification of bona fide microbial taxa in microbiomes derived from ancient and historical sa...
To date, characterization of ancient oral (dental calculus) and gut (coprolite) microbiota has been ...
Exploring the genetic diversity of microbes within the environment through metagenomic sequencing fi...
The microbes that live in and on our bodies play major roles in health and disease due to their symb...
YesAssigning metagenomic reads to taxa presents significant challenges. Existing approaches address ...
Assigning metagenomic reads to taxa presents significant challenges. Existing approaches address som...
Ancient metagenomics is a powerful tool for adding a deep-time dimension to biological projects. Bei...
The 1980s were very prolific years not only for music, but also for molecular biology and genetics, ...
Studies of human–associated microbial communities are increasingly integrated into biological anthro...
AbstractAssessing the taxonomic composition of metagenomic samples is an important first step in und...
Exploring the genetic diversity of microbes within the environment through metagenomic sequencing fi...
Metagenomics enables the study of complex microbial communities from myriad sources, including the r...
Metagenomics enables the study of complex microbial communities from myriad sources, including the r...
The field of palaeomicrobiology—the study of ancient microorganisms—is rapidly growing due to recent...
To date, characterization of ancient oral (dental calculus) and gut (coprolite) microbiota has been ...
The identification of bona fide microbial taxa in microbiomes derived from ancient and historical sa...
To date, characterization of ancient oral (dental calculus) and gut (coprolite) microbiota has been ...
Exploring the genetic diversity of microbes within the environment through metagenomic sequencing fi...
The microbes that live in and on our bodies play major roles in health and disease due to their symb...
YesAssigning metagenomic reads to taxa presents significant challenges. Existing approaches address ...
Assigning metagenomic reads to taxa presents significant challenges. Existing approaches address som...
Ancient metagenomics is a powerful tool for adding a deep-time dimension to biological projects. Bei...
The 1980s were very prolific years not only for music, but also for molecular biology and genetics, ...
Studies of human–associated microbial communities are increasingly integrated into biological anthro...
AbstractAssessing the taxonomic composition of metagenomic samples is an important first step in und...
Exploring the genetic diversity of microbes within the environment through metagenomic sequencing fi...