Local Field Potential, Relationship to BOLD Signal

Blood oxygen level-dependent (BOLD) functional magnetic resonance imaging (fMRI) has rapidly become the leading research tool in cognitive neuroscience. Understanding how BOLD signal relates to activity of neural populations is crucial for constraining the interpretation of any fMRI in humans or animals. Here we review how the mean extracellular field potential (mEFP) recorded with extracellular electrodes samples different components of neural activity and how these components relate to the BOLD fMRI signal